… KT3 antibody specifi- bind PDGF AA but did bind PDGF BBwith high affinity ( K d cally detected
our KT3-flagged A chain in PDGF AA and AB, = 0.5 nM). Surprisingly, PDGF AB bound (3 …

… by two genes (PDGF-A and PDGF-B), resulting in three dimeric isoforms of proteins: PDGF-AA,
PDGF-BB, and PDGF-AB. The biologically actions of these growth factors are known to …

… growth factors in vitro (8-17), and growth factors pharmacologically applied to wounds can
accelerate in vivo repair (2, 3, 5, 6, 10, 18-23). Growth factors … and in tumor growth, consistent …

… Although our studies do not prove that changes in PDGF synthesis mediate the effects of
other growth factors, such as TGFP, on bone cell function, this may be possible, because …

… of PDGF-AA, we have studied the ability of NG2 to bind to a variety of different growth factors…
of NG2 for growth factors. Here we report that the NG2 core protein binds with high affinity to …

… growth factor (PDGF) to its cell surface receptors … 2A, the binding of 1251-PDGFAA to the
wPDGFR transfectant was competed by either unlabeled PDGF-AA or PDGF-BB in a dose-…

… growth factor (PDGF) has been suggested to have a significant role in wound healing. The
present work was aimed at studying the effects of PDGF-AA and PDGF-… of PDGF-AA or PDGF-…

… , PDGF-AA may regulate other factors advantageous to tumor growth, including other
angiogenic factors; and (b) in addition to the indirect angiogenic effect using VEGF, PDGF-AA itself …

… but enhanced the delayed growth responses to these growth factors by 16.0-, … PDGF-AA
had no effect on these synergistic responses and exogenous PDGF-AA did not increase growth …

… The two chains can combine to three different dimcric isoforms, PDGFAA, PDGF-AB anrl
PDGF-BB [l,2,§]. It is generally accepted that agonist-mediated incecascs in cytosolic calcium in …