… These results proved that: (i) PDGF-AA enhances cell replication by accelerating cell recycle
and inducing the quiescent cells into the proliferation portion of cell cycle. (ii) PDGF-AA is a …

… -2 cells, and in the study conducted on osteblasts from a single patient, PDGF AA (at both
doses utilized) and BB (only at the lower dose utilized) significantly stimulate cell migration. …

… It decreased both PDGF-AA-mediated cell migration and thymidine incorporation. Our … the
response of osteoblastic cells to PDGFAA by decreasing the binding of PDGF-AA to its receptor…

… of fetal rat calvarial osteoblastic cells, we found that PDGF significantly inhibited mineralized
… of PDGF enhanced expression of histone, which is associated with cell proliferation, and sup…

… regulate PDGF-AA synthesis in bone cells are critical to our understanding of its role in bone
cell … In conclusion, the present studies demonstrate that PDGFAA and -BB stimulate PDGF-A …

… Previous studies have shown that PDGF-AA can be secreted by osteoblast cells, and its …
In conclusion, this study demonstrated that PDGF-AA increases cell-to-cell communication in …

… , our results suggest that PDGFAA has the … osteoblastic bone cells consistently expressed
the PDGF-A gene; both explanted and cloned osteoblastic cells were shown to produce PDGF; …

… osteoprogenitor cell zones, and that PDGFAA and -BB actually exert inhibitory effects on
osteoblast differentiation, determined as changes in the percent forming bone, and osteoblast …

… PHO cells were stimulated by both PDGF AA and BB, in a dose dependent manner (Fig.
lA, B). The concentration of lOng/ml was found to produce a maximal stimulatory response for …

… further confirmed that PDGF-AA-mediated … PDGF-AA promoted gap junction formation in
the osteoblast lineage through p-Akt signaling, which helped to understand the role of PDGF-AA …