… Thus, we inferred that PDGF-AA might induce Cx43 expression through the PI3K/Akt
signaling pathway to activate the CREB phosphorylation, thereby affecting Cx43 transcription by …

… recombinant PDGF-AA to explore the effects of PDGF-AA on … To examine the effects of
PDGF-AA on cell communication, … PI3K/Akt signaling primarily involved in the process of PDGF-…

… ASC’s transmigration significantly increased towards PDGF AA at 50 ng and only showed
… significantly enhanced by PDGF-BB via the PI3K pathway. Our data support that PI3K is an …

… of PDGF- AA … of PDGF- AA on DPSC migration and proliferation. A scrape loading/dye
transfer assay was applied to evaluate GJIC triggered by PDGF- AA, a PI3K/Akt signalling pathway …

… of NSCs through secretion of PDGF-AA. In the present study, we detected the expression
of PDGF-AA mRNA in B104 cells and the high level of PDGF-AA protein in B104CM. Most …

… Thus, we speculate that the PDGFR-β/PI3K/AKT signaling pathway might be involved in
the PDGF-BB induced proliferation of fibroblasts and their transformation into CFs. …

… As shown in Figure 3, the PI3K (LY290042) and Erk1/Erk2 (PD98059) inhibitors significantly
inhibited MSC proliferation induced by PDGFAA and PDGF-BB, while the MAPK (SB203580…

… confirmed that PDGF-AA-mediated gap junction formation occurred via the activation of
PI3K/Akt signaling. Taking together, our results provided evidences that PDGF-AA promoted gap …

… that the PI3K/Akt signaling pathway is important for PDGF-BB … PDGF signaling mediated
physiological changes of EPCs. … -β, PI3K, and Akt are important participants following PDGF …

… the PI3K/AKT/ eNOS pathway is a downstream effector of PDGF-AA and provided direct
evidence that PI3K/AKT/eNOS expression is downregulated by the loss of PDGF-AA function in …