… PDGFRs in response to PDGF-AB resulted in P receptor activation. Since wild type receptor
… domain (16), we examined P receptor tyrosine phosphorylation in response to PDGF-AB. To …

… include overexpression or amplification of PDGF receptors (PDGFRs), gain of function point
… their receptors by specific DNA aptamers and ligand traps, or downregulate PDGFRs with …

… fact that all PDGF-A, PDGF-B, PDGFR-alpha or PDGFR-beta knockout are embryonic lethal
whereas heterozygous mice are viable’. PDGFs/PDGFRs axis is known to participate in the …

… To date, the role of PDGFR-β in EPCs still remains largely unknown. In this study, we
transfected PDGFR-β into spleen-derived EPCs and found that PDGFR-β over-expression …

… Binding is rapid, saturable and requires phosphorylation of the PDGFR at Y751, but does …
of the PDGFR are important for binding, we used an antibody to a small region of the receptor …

… in the human platelet-derived growth factor receptor (PDGFR) fi subunit have been mapped
… wild-type(WT) and mutant human PDGF receptor fi subunits in dog kidney epithelial cells. …

… factor receptor beta (PDGFRβ) on pericytes, it has been demonstrated that PDGF-B/PDGFRβ …
Relatively little is known, however, about the roles of PDGF-B/PDGFRβ interactions and …

… As the receptor kinase activity seems to be a major driver of … , we hypothesized that PDGFR
expression is required for mass … of PDGFRα and β is cell type specific: PDGFRβ expression is …

… prognostic significance of PDGF/ PDGFR-β immunohistochemistry in unselected NSCLC,
it … -B/ PDGFR-β, we sought to characterize the presence of PDGFR-β expression and gene …

… of their PDGFR-α or PDGFR-β receptors using … (PDGFR-α Y751 and Y1021, PDGFR-β
Y1018 and Y754) (data not shown). In each case we found that both PDGFR-α and PDGFR-β …