… receptor proteins on cell surfaces. We have previously reported that PEDF binds and stimulates
PEDF receptor (PEDF-… However, the PEDF binding site of PEDF-R and its involvement in …

… PEDF also increases the amount of membrane-bound TRAIL on cultured … PEDF-induced
tumor killing and TRAIL induction are abrogated by peroxisome proliferator-activated receptor γ …

… that PEDF induces death of endothelial cells through the activation of both receptor-… of
apoptosis in HUVECs involved other cell death molecules that are targeted much earlier in the …

… in the deregulated apoptotic pathways of malignant cells must first be fully characterized. …
are relevant to PEDF and cancer. Recently, a pathway that includes the PEDF receptor, PPARγ …

… hypoxia-induced cell death and the mechanisms are … receptors of PEDF, laminin receptor
(LR) and PEDF receptor (PEDFR) which express in a variety of cells including endothelial cells …

… depend on its interactions with cell-surface receptors: PEDF receptor (PEDFR; encoded by
… Similarly, a proportion of cultured glioma cells undergo cell death after exposure to PEDF in …

… derived factor (PEDF) acts as a survival factor for cerebellar granule cell neurons in culture,
… have examined effects of PEDF on apoptotic cell death. We find that the granule cells die of …

… effects were mediated by the PEDF receptor (PEDF-R), … domain of PEDF targeted these same
cell death pathways in … of PEDF in photoreceptors, we analyzed cell death pathways in rd1 …

… -R receptors in plasma membranes. Such interactions trigger changes … PEDF/PEDF-R
interactions attenuate the cell death process in retinal cells and particularly in PRs undergoing cell …

… However, Preeti Subramanian and his colleagues reported that pigment PEDF prevents
retinal cell death via PEDF-R and PLA2 enzymatic activity, and it is critical for upregulating Bcl-2 …