Diverse oncogenic fusions and distinct gene expression patterns define the genomic landscape of pediatric papillary thyroid carcinoma
… the genomes and transcriptomes of pediatric and adult papillary thyroid carcinoma, with …
for understanding the biology, diagnosis, and treatment of advanced disease in children. …
for understanding the biology, diagnosis, and treatment of advanced disease in children. …
Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations
A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
… In this review, we focus on papillary thyroid carcinoma (PTC), which represents … genetic
landscape of adult and pediatric PTC, discussing post-Chernobyl and post-Fukushima pediatric …
landscape of adult and pediatric PTC, discussing post-Chernobyl and post-Fukushima pediatric …
The Evolving Genomic Landscape of Pediatric Papillary Thyroid Cancer
JC Ricarte-Filho, AT Franco - Current Opinion in Endocrine and Metabolic …, 2023 - Elsevier
… genetic and molecular features of pediatric and adult tumors share many similar characteristics,
but the prevalence of gene fusions is much higher in pediatric … pediatric papillary thyroid …
but the prevalence of gene fusions is much higher in pediatric … pediatric papillary thyroid …
Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma
… Although it is generally thought to exhibit similar molecular aberrancies as their counterpart
tumors in adults, the pan-genomic landscape of clinically aggressive pPTCs has not been …
tumors in adults, the pan-genomic landscape of clinically aggressive pPTCs has not been …
Molecular landscape of pediatric thyroid cancer: a review
P Guleria, R Srinivasan, C Rana, S Agarwal - Diagnostics, 2022 - mdpi.com
… carcinoma (PDTC), and anaplastic thyroid carcinoma (… of thyroid follicular cells [1], and
papillary thyroid carcinoma (PTC) forms the bulk (>90%), followed by follicular thyroid carcinoma (…
papillary thyroid carcinoma (PTC) forms the bulk (>90%), followed by follicular thyroid carcinoma (…
Evaluation of the molecular landscape of pediatric thyroid nodules and use of a multigene genomic classifier in children
… the finding of recurrent DICER1 variants should help inform individualized treatment for
patients and expand the understanding of the genetic mechanisms of thyroid tumors in children. …
patients and expand the understanding of the genetic mechanisms of thyroid tumors in children. …
Genomic landscape of sporadic pediatric differentiated thyroid cancers: a systematic review and meta-analysis
S Satapathy, C Bal - … of Pediatric Endocrinology and Metabolism, 2022 - degruyter.com
… Most of the studies evaluating the same, in the setting of paediatric population, have small
… of paediatric DTCs, it is essential to understand the underlying genetic landscape so as to …
… of paediatric DTCs, it is essential to understand the underlying genetic landscape so as to …
Genetic landscape of papillary thyroid carcinoma in the Chinese population
J Liang, W Cai, D Feng, H Teng, F Mao… - The Journal of …, 2018 - Wiley Online Library
… In this study, we defined the genetic landscape of PTC in the Chinese population. A total of
88.7% of patients were identified with oncogenic driver genetic variants, providing important …
88.7% of patients were identified with oncogenic driver genetic variants, providing important …
Genetic alterations landscape in paediatric thyroid tumours and/or differentiated thyroid cancer: Systematic review
MSA de Sousa, IN Nunes, YP Christiano… - Reviews in Endocrine …, 2024 - Springer
… genetic landscape, support a significantly lower rate of the BRAF V600E mutation in PTC
in paediatric … and RAS-score (BRS) for paediatric thyroid carcinoma [121], the authors also …
in paediatric … and RAS-score (BRS) for paediatric thyroid carcinoma [121], the authors also …
Papillary thyroid carcinoma: current position in epidemiology, genomics, and classification
AK Lam - Papillary Thyroid Carcinoma: Methods and Protocols, 2022 - Springer
… Approximately 5% of papillary thyroid carcinomas are noted in childhood … papillary thyroid
carcinomas are found in this age group [8, 9]. The sporadic cases of thyroid cancer in children, …
carcinomas are found in this age group [8, 9]. The sporadic cases of thyroid cancer in children, …
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