Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck …

B Burtness, KJ Harrington, R Greil, D Soulières… - The Lancet, 2019 - thelancet.com
… plus a platinum and 5-fluorouracil (pembrolizumab with … superiority of pembrolizumab alone
and of pembrolizumab with … margin: 1·2) of pembrolizumab alone and pembrolizumab with …

Pembrolizumab alone or with chemotherapy for recurrent/metastatic head and neck squamous cell carcinoma in KEYNOTE-048: subgroup analysis by programmed …

B Burtness, D Rischin, R Greil, D Soulières… - Journal of Clinical …, 2022 - ascopubs.org
… KEYNOTE-048 investigated pembrolizumab monotherapy and pembrolizumab plus
chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma. Efficacy was …

[HTML][HTML] Pembrolizumab alone or with chemotherapy for recurrent or metastatic head and neck squamous cell carcinoma: Health-related quality-of-life results from …

D Rischin, KJ Harrington, R Greil, D Soulieres… - Oral oncology, 2022 - Elsevier
… had pathologically confirmed squamous cell carcinoma of the … pembrolizumab alone (pembrolizumab
200 mg every 3 weeks [Q3W]), pembrolizumab-chemotherapy (pembrolizumab

Pembrolizumab plus chemotherapy versus chemotherapy alone for first-line treatment of advanced oesophageal cancer (KEYNOTE-590): a randomised, placebo …

JM Sun, L Shen, MA Shah, P Enzinger, A Adenis, T Doi… - The Lancet, 2021 - thelancet.com
… to pembrolizumab plus … ), pembrolizumab plus chemotherapy was superior to placebo plus
chemotherapy for overall survival in patients with oesophageal squamous cell carcinoma and …

Pembrolizumab

L Khoja, MO Butler, SP Kang, S Ebbinghaus… - … for immunotherapy of …, 2015 - Springer
… non-small cell lung … pembrolizumab alone and in combination for melanoma, NSCLC, and
other tumor types. In this article, we review the efficacy and toxicity profile of pembrolizumab

Pembrolizumab with or without chemotherapy in recurrent or metastatic head and neck squamous cell carcinoma: updated results of the phase III KEYNOTE-048 study

KJ Harrington, B Burtness, R Greil… - Journal of Clinical …, 2023 - ascopubs.org
… observed with pembrolizumab alone and pembrolizumab-… Retreatment with pembrolizumab
provided benefit in some … of pembrolizumab alone versus cetuximab-chemotherapy and …

Open-label, single-arm phase II study of pembrolizumab monotherapy as first-line therapy in patients with advanced clear cell renal cell carcinoma

DF McDermott, JL Lee, GA Bjarnason… - Journal of Clinical …, 2021 - ascopubs.org
… The safety profile of pembrolizumab monotherapy in the … of pembrolizumab in other tumor
types. Commonly reported grade 3/4 treatment-related AEs associated with pembrolizumab

First-line treatment for patients with advanced non-small cell lung carcinoma and high PD-L1 expression: pembrolizumab or pembrolizumab plus chemotherapy

Y Zhou, Z Lin, X Zhang, C Chen, H Zhao… - … for immunotherapy of …, 2019 - Springer
… trials that compared pembrolizumab plus chemotherapy or pembrolizumab alone with … ,
with the search terms including pembrolizumab, non–small cell lung cancer, and randomized …

Safety and efficacy of pembrolizumab in combination with acalabrutinib in advanced head and neck squamous cell carcinoma: phase 2 proof-of-concept study

MH Taylor, CB Betts, L Maloney, E Nadler, A Algazi… - Clinical Cancer …, 2022 - AACR
… Clinical data from a phase 2 study investigating the combination of the BTK inhibitor
acalabrutinib and PD-1 inhibitor pembrolizumab compared with pembrolizumab alone were …

[HTML][HTML] Pembrolizumab plus chemotherapy for squamous non–small-cell lung cancer

L Paz-Ares, A Luft, D Vicente, A Tafreshi… - … England Journal of …, 2018 - Mass Medical Soc
… plus chemotherapy has shown a high level of activity as compared with chemotherapy alone
whether pembrolizumab plus chemotherapy has greater efficacy than pembrolizumab alone