Pemetrexed combination therapy in the treatment of non–small cell lung cancer

R Rosell, L Crinó - Seminars in oncology, 2002 - Elsevier
… synergistic combinations that should be explored include pemetrexedpemetrexed need
to be investigated, including the potential role of TS messenger RNA. In summary, pemetrexed

Pemetrexed with platinum combination as a backbone for targeted therapy in non–small-cell lung cancer

TE Stinchcombe, H Borghaei, SS Barker, JA Treat… - Clinical Lung Cancer, 2016 - Elsevier
… Thus, the pemetrexed–platinum backbone provides an attractive option for combination with
… of pemetrexed–platinum as a backbone for combination with targeted therapies for NSCLC. …

Phase II study of pemetrexed in combination with carboplatin in the first‐line treatment of advanced nonsmall cell lung cancer

RG Zinner, FV Fossella, GW Gladish… - Cancer …, 2005 - Wiley Online Library
pemetrexed and its activity against a wide range of solid tumors.7 Another early Phase I
study established the safety of pemetrexed in combination … from Australia, pemetrexed as first-…

Role of pemetrexed and platinums combination in patients with non-small cell lung cancer

M Chen, W Shao, J He, D Wang - Current Drug Targets, 2010 - ingentaconnect.com
… of advanced non-small cell lung cancer (NSCLC), the … cytotoxic agent, pemetrexed, and its
combination with platinums … ) to pemetrexed/platinum in NSCLC, and the role of pemetrexed/…

Pemetrexed for the treatment of non-small-cell lung cancer

C Manegold, G Schmid-Bindert… - Expert Review of …, 2009 - Taylor & Francis
… The Phase III Zactima Efficacy with Alimta in Lung cancer (ZEAL) trial is currently ongoing
to study the effect of pemetrexed combined with vandetanib in patients with locally-advanced …

Pemetrexed combined with paclitaxel in patients with advanced or metastatic non-small-cell lung cancer: a phase I-II trial

GP Stathopoulos, J Dimitroulis, M Toubis, C Katis… - Lung Cancer, 2007 - Elsevier
Pemetrexed, a novel multi-targeted agent established for the treatment of mesothelioma, …
-cell lung cancer (NSCLC). In the present trial we investigated pemetrexed in combination with …

[HTML][HTML] Review of the pemetrexed and gemcitabine combination in patients with advanced-stage non-small cell lung cancer

C Monnerat, T Le Chevalier - Annals of Oncology, 2006 - Elsevier
… Dark, GG Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in
advanced non-small cell lung cancer: a multicenter, randomized, phase II trial Clin Cancer Res 11…

Comparison of pemetrexed plus cisplatin with other first-line doublets in advanced non-small cell lung cancer (NSCLC): a combined analysis of three phase 3 trials

J Treat, GV Scagliotti, G Peng, MJ Monberg… - Lung cancer, 2012 - Elsevier
… The primary objective of the current combined analysis of three large phase 3 trials was
to determine the comparability (overall and by histology) of pemetrexed–cisplatin with other …

Pemetrexed monotherapy versus pemetrexed plus platinum combination as second-line treatment for advanced non-small cell lung cancer

Y Zhang, Z Chen, S Lu - Chinese medical journal, 2009 - mednexus.org
… Inthisreport,wecomparetheefectsandtoxicities in advanced NSCLC patients treated with
pemetrexed monotherapyversuspemetrexedplusplatinum combination agentso as co provide a …

… II study of pemetrexed in combination with cisplatin or carboplatin as first-line therapy for patients with locally advanced or metastatic non–small-cell lung cancer

WHW Schuette, A Gröschel, M Sebastian, S Andreas… - Clinical lung cancer, 2013 - Elsevier
… 11, 12 suggest that pemetrexed plus carboplatin is a tolerable … and efficacy of pemetrexed
combined with either cisplatin or … pemetrexed plus cisplatin or pemetrexed plus carboplatin. …