Glucagon-like peptide-1: a focus on neurodegenerative diseases

M Grieco, A Giorgi, MC Gentile, M d'Erme… - Frontiers in …, 2019 - frontiersin.org
… a link between T2D and neurodegenerative disease such as Parkinson’s disease (PD)
and Alzheimer’s Disease (AD). Neurodegenerative diseases have a considerable physical, …

[HTML][HTML] Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment

KO Kopp, EJ Glotfelty, Y Li, NH Greig - Pharmacological research, 2022 - Elsevier
neurodegenerative diseases, … neurodegenerative disease treatment. We propose that
repurposing already-approved GLP-1R agonists for the treatment of neurodegenerative diseases

Novel GLP-1 (glucagon-like peptide-1) analogues and insulin in the treatment for Alzheimer's disease and other neurodegenerative diseases

V Calsolaro, P Edison - CNS drugs, 2015 - Springer
1 analogues such as liraglutide, exenatide and lixisenatide in neurodegenerative diseases.
… could play a role in some neurodegenerative diseases, such as AD, PD, Huntington’s …

Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases

SD Chen, YC Chuang, TK Lin, JL Yang - European journal of …, 2023 - Elsevier
… Aging is a crucial risk factor for common neurodegenerative diseases, such as Alzheimer's
disease (AD) and Parkinson's disease (PD). Limited options are available for the treatment of …

Peptide aggregation in neurodegenerative disease

RM Murphy - Annual review of biomedical engineering, 2002 - annualreviews.org
… that these aggregates play key roles in many diseases. In this review, wefocus attention on
… three feared neurodegenerative diseases: Alzheimer's,“mad cow,” and Huntington's disease, …

The role of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in diabetes-related neurodegenerative diseases

D Cheng, S Yang, X Zhao, G Wang - Drug design, development …, 2023 - Taylor & Francis
… treatment of type 1 diabetes mellitus in … -1 RA has the potential to treat neurodegenerative
diseases, particularly in diabetes-related Alzheimer’s disease (AD) and Parkinson’s disease (…

[HTML][HTML] Peptide based therapeutics and their use for the treatment of neurodegenerative and other diseases

MH Baig, K Ahmad, M Saeed, AM Alharbi… - Biomedicine & …, 2018 - Elsevier
peptides and their applications for the management of different diseases, but with focus on
neurodegenerative diseases. … QBP1, a polyQ binding peptide 1, was identified using a phage …

The role of β-amyloid peptide in neurodegenerative diseases

AV Maltsev, S Bystryak, OV Galzitskaya - Ageing research reviews, 2011 - Elsevier
… of disease and the mechanisms triggering conformational changes in β-amyloid peptide
and their role in the pathogenesis of neurodegenerative diseases. In addition, we discuss a …

Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases

C Hölscher - Journal of Endocrinology, 2014 - joe.bioscientifica.com
… -like peptide 1 (GLP-1) facilitates insulin release during episodes of hyperglycaemia and
has several additional properties to overcome insulin desensitisation made GLP-1 an ideal …

Peptidomic approaches and observations in neurodegenerative diseases

B Muqaku, P Oeckl - International journal of molecular sciences, 2022 - mdpi.com
disease-related pathological conditions. One important example in neurodegenerative
diseases is the accumulation of amyloid-beta peptides (Aβ) in the brain of Alzheimer’s disease (…