Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA–B27 allotypes
RB Schittenhelm, TCCLK Sian… - Arthritis & …, 2015 - Wiley Online Library
… for a panel of HLA–B27–specific peptides. For each peptide, the predominant precursor ion
… ion library containing information on all HLA–B27– specific peptides identified in this study. …
… ion library containing information on all HLA–B27– specific peptides identified in this study. …
HLA B27 in health and disease: a double‐edged sword?
P Bowness - Rheumatology, 2002 - academic.oup.com
… this HLA B27/peptide combination and does HLA B27 … of the HLA B27 heavy chain in peptide
binding and HLA B27 folding, … complexes of HLA B27, refolded with specific peptides. Such …
binding and HLA B27 folding, … complexes of HLA B27, refolded with specific peptides. Such …
HLA‐B27: a registry of constitutive peptide ligands
JA Lopez de Castro, I Alvarez, M Marcilla… - Tissue …, 2004 - Wiley Online Library
… peptide sequencing, X-ray diffraction, and other studies, the peptide specificity of HLA-B27 …
The major feature of HLA-B27 ligands is an almost absolute restriction for R2, which is the …
The major feature of HLA-B27 ligands is an almost absolute restriction for R2, which is the …
A subset of HLA-B27 molecules contains peptides much longer than nonamers.
RG Urban, RM Chicz, WS Lane… - Proceedings of the …, 1994 - National Acad Sciences
… In this paper the repertoire of peptides bound to HLA-B27 molecules in vivo has been … of
the HLA-B27 population and a more typical mAb (ME1) that reacts with all cell surface HLA-B27 …
the HLA-B27 population and a more typical mAb (ME1) that reacts with all cell surface HLA-B27 …
The immunobiology of HLA-B27: variations on a theme
RA Colbert - Current molecular medicine, 2004 - ingentaconnect.com
… In studies aimed at understanding how unique structural features of HLA-B27 influence
peptide selection [17], we discovered that HC folding was unusually slow in comparison to other …
peptide selection [17], we discovered that HC folding was unusually slow in comparison to other …
Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide.
JM Brooks, RJ Murray, WA Thomas… - The Journal of …, 1993 - rupress.org
… B27 subtypes, we sought to determine the epitope specificity of these responses using
synthetic peptides… In an initial series of experiments, we screened a panel of 15-mer peptides (…
synthetic peptides… In an initial series of experiments, we screened a panel of 15-mer peptides (…
Modulation at multiple anchor positions of the peptide specificity of HLA–B27 subtypes differentially associated with ankylosing spondylitis
JR Lamas, A Paradela, F Roncal… - … : Official Journal of …, 1999 - Wiley Online Library
… The strategy used in this study to analyze the peptide specificity of HLA–B27 was an … the
peptide specificity of HLA–B27 as measured in the present study closely reflects its specificity in …
peptide specificity of HLA–B27 as measured in the present study closely reflects its specificity in …
Peptide binding to empty HLA-B27 molecules of viable human cells
RJ Benjamin, JA Madrigal, P Parham - Nature, 1991 - nature.com
… feeding” assay we find that a significant proportion of cell-associated HLA-B27 molecules
bind peptide with allelic specificity. Peptides seem to bind to empty HLA-B27 molecules that …
bind peptide with allelic specificity. Peptides seem to bind to empty HLA-B27 molecules that …
The peptide binding specificity of HLA-B27 subtypes
… peptide binding was measured by the HLA class I alpha chain refolding assay. The data
obtained indicated that the B27 subtypes tested can bind a common set of peptides … by all B27 …
obtained indicated that the B27 subtypes tested can bind a common set of peptides … by all B27 …
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