… Tapasin is thought to play a key role in optimization of the cargo of bound peptides,
although HLA-B27 is less dependent on tapasin than other alleles such as B*4402 (12). These …

… for a panel of HLA–B27–specific peptides. For each peptide, the predominant precursor ion
… ion library containing information on all HLA–B27– specific peptides identified in this study. …

… this HLA B27/peptide combination and does HLA B27 … of the HLA B27 heavy chain in peptide
binding and HLA B27 folding, … complexes of HLA B27, refolded with specific peptides. Such …

… peptide sequencing, X-ray diffraction, and other studies, the peptide specificity of HLA-B27 …
The major feature of HLA-B27 ligands is an almost absolute restriction for R2, which is the …

… In this paper the repertoire of peptides bound to HLA-B27 molecules in vivo has been … of
the HLA-B27 population and a more typical mAb (ME1) that reacts with all cell surface HLA-B27 …

… In studies aimed at understanding how unique structural features of HLA-B27 influence
peptide selection [17], we discovered that HC folding was unusually slow in comparison to other …

… B27 subtypes, we sought to determine the epitope specificity of these responses using
synthetic peptides… In an initial series of experiments, we screened a panel of 15-mer peptides (…

… The strategy used in this study to analyze the peptide specificity of HLA–B27 was an … the
peptide specificity of HLA–B27 as measured in the present study closely reflects its specificity in …

… feeding” assay we find that a significant proportion of cell-associated HLA-B27 molecules
bind peptide with allelic specificity. Peptides seem to bind to empty HLA-B27 molecules that …

… peptide binding was measured by the HLA class I alpha chain refolding assay. The data
obtained indicated that the B27 subtypes tested can bind a common set of peptides … by all B27 …