… dendritic cells (DCs) were generated ex vivo and were pulsed with MAGE-3 peptide, … Patients
were immunized with DC pulsed with MAGE-3 peptide every 3 weeks at four times. Twelve …

… whether vaccination can augment such responses. We found that a dendritic cell vaccine
led to an … Thus, peptide vaccination with functionally mature dendritic cells may promote the …

… naive DC for efficient CD8 + T cell priming in vitro; 2) exosomes … I/peptide complexes to DC
for efficient CTL activation in vivo. … The role of dendritic cells (DC) 4 as regulators of the T cell …

… in the peripheral blood mononuclear cells of the six patients … , T-cell responses to antigens
not used for vaccinations, such as … This study shows that MUC1 peptide–pulsed dendritic cells …

… peptide-loaded dendritic cell (DC) vaccination … vaccines loaded with MHC class I and II-restricted
peptides were applied subcutaneously at 2-week intervals for the first five vaccinations …

… result in superior T-cell sensitization as measured by de novo target-cell recognition and DTH
… ROA for mature DC vaccines. DENDRITIC CELL (DC) vaccines show promise for treating …

… -associated antigenic peptides were previously shown to activate specific T cells and …
four to six vaccinations in half of the patients led to p53-peptide–specific T-cell responses in …

… Based on these experiences, we propose a DC or peptide vaccine combined with
chemotherapy as a new treatment modality for gliomas. The second point is how to overcome the …

… immunity and increased infiltration of activated CD8 + effector T-cells … vaccination strategy
for DC-based vaccines and also a unique vaccine product for stimulating and enhancing T-cell …

… peptide vaccines by triggering TLR signaling in DCs. We are therefore investigating whether
by using TLR agonists as vaccine … the differentiation of naïve T cells towards either Th1, Th2…