… Indeed, PNN abnormalities have been observed in post-mortem brain tissues of patients …
evidence for PNN abnormalities in CNS disorders associated with altered network function and …

… The perineuronal net (PNN) is a highly latticed extracellular … PNN undergoes abnormal
changes during aging and in … and summarizes how PNN abnormalities contribute to aging and …

Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around
certain neurons in the CNS during development and control plasticity in the adult CNS. They …

… Perineuronal nets (PNNs) were shown to be markedly altered in subjects with schizophrenia…
PNN abnormalities in schizophrenia, the potential functional impact of such abnormalities …

… In a subpopulation of neurons, the ECM condenses to superstructures called perineuronal
nets (PNNs) that surround synapses. Camillo Golgi described PNNs a century ago, yet their …

… In the brain, CS proteoglycans are highly concentrated in perineuronal nets (PNNs), which
… In T1KO, we observed abnormalities in several behavioral tests, including the open-field test…

… b | The structure of the perinodal ECM is similar to that of perineuronal nets (PNNs), with
chondroitin sulfate proteoglycans (CSPGs) — particularly brevican, neurocan and versican — …

… Abnormal perineuronal nets, as observed in the postmortem patient brain, may thus underlie
the vulnerability and functional impairment of pivotal inhibitory circuits in schizophrenia. …

… that ECM abnormalities may contribute to a … abnormalities in schizophrenia, the main focus
of these authors’ studies, is discussed, with particular emphasis on loss of perineuronal nets (…

… deficits in extracellular matrix structures called perineuronal nets (PNNs), particularly in PFC…
Our results indicate MIA causes region specific developmental abnormalities in PNNs in the …