Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development, and …

Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that surround
the soma and proximal dendrites of certain neurons in the central nervous system, …

Perineuronal nets regulate the inhibitory perisomatic input onto parvalbumin interneurons and γ activity in the prefrontal cortex

H Carceller, R Guirado, E Ripolles-Campos… - Journal of …, 2020 - Soc Neuroscience
… the extracellular matrix, the perineuronal nets (PNNs). PNNs … neural oscillations that depend
on these cells. These findings are relevant to understand the role of PNNs in the adult brain

Removal of perineuronal nets unlocks juvenile plasticity through network mechanisms of decreased inhibition and increased gamma activity

KK Lensjø, ME Lepperød, G Dick… - Journal of …, 2017 - Soc Neuroscience
… unit activity and a remarkable potentiation of gamma oscillations. Our results demonstrate
how PNNs may be involved directly in stabilizing the neural network. Moreover, the immediate …

Perineuronal nets, inhibitory interneurons, and anxiety-related ventral hippocampal neuronal oscillations are altered by early life adversity

S Murthy, GA Kane, NJ Katchur, PSL Mejia… - Biological …, 2019 - Elsevier
… Several studies have suggested that neuronal oscillations in the theta frequency (4–12 Hz)
… by specialized extracellular matrix structures termed perineuronal nets (PNNs). PNNs are …

Fast oscillatory activity in the anterior cingulate cortex: dopaminergic modulation and effect of perineuronal net loss

P Steullet, JH Cabungcal, M Cuénod… - Frontiers in cellular …, 2014 - frontiersin.org
… These high-frequency oscillations in the ACC relied on both phasic inhibitory and excitatory
… of these oscillations was significantly enhanced after degradation of the perineuronal nets (…

Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories

JC Wingert, JD Ramos, SX Reynolds… - Journal of …, 2024 - jneurosci.org
… removal of key extracellular matrix structures called perineuronal nets 26 (PNNs) within the
mPFC … within the mPFC impairs the coupling of oscillations between the mPFC and 28 dorsal …

Perineuronal nets in brain physiology and disease

D Testa, A Prochiantz, AA Di Nardo - Seminars in cell & developmental …, 2019 - Elsevier
Perineuronal nets (PNNs) in the brain are condensed … We further discuss the role of
PNNs in brain disorders such as … to alter brain physiology and counter brain dysfunction. …

Removal of perineuronal nets disrupts recall of a remote fear memory

EH Thompson, KK Lensjø… - Proceedings of the …, 2018 - National Acad Sciences
… In addition, we investigated whether synchronized theta oscillations between V2L and BLA
is present during recent memory retrieval. In accordance with previous work (17), we found …

Perineuronal nets protect fast-spiking interneurons against oxidative stress

JH Cabungcal, P Steullet, H Morishita… - Proceedings of the …, 2013 - National Acad Sciences
… To study the effect of PNN degradation, we recorded and analyzed oscillations induced by
… The effects of ChABC and GBR treatment and their interaction on the power of oscillations