Perineuronal nets in brain physiology and disease

D Testa, A Prochiantz, AA Di Nardo - Seminars in cell & developmental …, 2019 - Elsevier
… to alter brain physiology and counter brain dysfunction. … brain functions and its ensuing
implication in several brain … our understanding of brain physiology and animal behavior and …

Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
… as a promising target to understand the physiology and pathologic conditions of the CNS. …
of perineuronal nets in the mouse brain. Representative coronal slices of mouse brain stained …

[HTML][HTML] An extracellular perspective on CNS maturation: perineuronal nets and the control of plasticity

D Carulli, J Verhaagen - International Journal of Molecular Sciences, 2021 - mdpi.com
… , in the adult brain, the expression of perineuronal nets is … how perineuronal nets contribute
to the maturation of brain … adult brain plasticity and memory processes in physiological

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

JW Fawcett, T Oohashi, T Pizzorusso - Nature Reviews Neuroscience, 2019 - nature.com
Perineuronal nets (PNNs) are extracellular matrix (ECM) chondroitin sulfate proteoglycan (CSPG)-containing
structures that surround the soma and dendrites of various mammalian …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
physiological functioning of the brain, such as learning and memory as well as pathologies
underlying brain … by ECM molecules into our understanding of brain signaling processes. …

[HTML][HTML] Perineuronal nets and their role in synaptic homeostasis

M Bosiacki, M Gąssowska-Dobrowolska… - International journal of …, 2019 - mdpi.com
… of perineuronal net impairment. Furthermore, we discuss the participation of PNNs in brain
… signaling in order to properly understand the normal physiological functioning of the brain, …

The perineuronal net and the control of CNS plasticity

D Wang, J Fawcett - Cell and tissue research, 2012 - Springer
… in different species and in different physiological and experimental models. These ideas …
, mainly associated with myelinated axons in the brain and spinal cord and co-localized with …

[HTML][HTML] Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
… Overall, changes in PNNs and PV neurons after physiological stimuli appear to be specific
to the physiological stimulus, brain region, and the circuits in which PNN-surrounded neurons …

Physiological Roles of Perineuronal Nets in Cerebellar Functions

M Hirono - Cerebellum as a CNS Hub, 2021 - Springer
… and contribute to regulating neural plasticity in brain areas, including the visual cortex and
… This chapter focuses on recent evidence on the physiological roles of PNNs, which enwrap …

Perineuronal nets: plasticity, protection, and therapeutic potential

AC Reichelt, DJ Hare, TJ Bussey, LM Saksida - Trends in neurosciences, 2019 - cell.com
… The relationship between neurons and perineuronal nets (PNNs) is attracting attention
as a central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …