… b | The structure of the perinodal ECM is similar to that of perineuronal nets (PNNs), with
chondroitin sulfate proteoglycans (CSPGs) — particularly brevican, neurocan and versican — …

… The role of perineuronal nets is not fully elucidated yet. Perineuronal nets may play a beneficial
role … recent evidence concerning the significance of the occurrence of perineuronal nets. …

… of PNN expression and their cell-type specificity is limited. We … We have identified several
distinct cell types associated with … in expression, cell-type specificity and morphology. This …

… Perineuronal nets (PNNs) are specialized structures of the extracellular matrix that
surround the soma and proximal dendrites of certain neurons in the central nervous system, …

… Finally, we have demonstrated that the cell-specific composition of perineuronal nets is
mediated, at least in part, by variation in aggrecan glycosylation. The differential glycosylation of …

… molecules, self-assembling into aggregate structures called perineuronal nets (PNNs) [12,13,…
While diffuse CNS ECM surrounds all structures in the CNS, perineuronal nets (PNNs) with …

… to net-associated neurons. Here, we show that neurons ensheathed by a perineuronal net
in the … by lipofuscin accumulation than neurons without a net both in normal-aged brain and …

… by the appearance of perineuronal nets (PNNs) around the cell body and dendrites of many
… To elucidate the role played by neurons and glial cells in constructing PNNs, we studied the …

… cellular contributions to their formation, which is studied herein using primary cortical cell …
glia, PNN components impacted by this cell type were identified. Effects of depolarizing KCl …

… Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized extracellular …