An extracellular perspective on CNS maturation: perineuronal nets and the control of plasticity

D Carulli, J Verhaagen - International Journal of Molecular Sciences, 2021 - mdpi.com
… is remarkably dynamic, changing its plasticity-associated conditions, including … perineuronal
nets contribute to the maturation of brain circuits and the regulation of adult brain plasticity

The perineuronal net and the control of CNS plasticity

D Wang, J Fawcett - Cell and tissue research, 2012 - Springer
Perineuronal nets (PNNs) are reticular structures that … The involvement of PNNs in neuronal
plasticity has been … development and plasticity. The PNN is an important regulator of CNS …

Perineuronal nets: plasticity, protection, and therapeutic potential

AC Reichelt, DJ Hare, TJ Bussey, LM Saksida - Trends in neurosciences, 2019 - cell.com
… The ECM has emerged as an important participant in synaptic plasticity, and in particular
the structures comprised of condensed ECM known as perineuronal nets (PNNs); [ …

Casting a wide net: role of perineuronal nets in neural plasticity

BA Sorg, S Berretta, JM Blacktop… - Journal of …, 2016 - Soc Neuroscience
Perineuronal nets (PNNs) are unique extracellular matrix structures that wrap around certain
neurons in the CNS during development and control plasticity … , control plasticity, and on the …

Perineuronal nets suppress plasticity of excitatory synapses on CA2 pyramidal neurons

KE Carstens, ML Phillips, L Pozzo-Miller… - Journal of …, 2016 - Soc Neuroscience
… Here, we present evidence that perineuronal nets (PNNs), a specialized extracellular …
plasticity-resistant excitatory CA2 synapses; thus, PNNs play a role in restricting synaptic plasticity

Neuron‐glia interactions in neural plasticity: contributions of neural extracellular matrix and perineuronal nets

E Dzyubenko, C Gottschling, A Faissner - Neural plasticity, 2016 - Wiley Online Library
plasticity was previously reviewed [19], and in this paper we will focus on the role of ECM in
neural plasticity. … ECM develops into a specific formation termed perineuronal nets [20, 21]. …

[PDF][PDF] Perineuronal net, CSPG receptor and their regulation of neural plasticity

QL Miao, Q Ye, XH Zhang - Sheng Li Xue Bao, 2014 - researchgate.net
… Distribution of pyramidal cells associated with perineuronal nets in … Diffuse perineuronal
nets and modified pyramidal cells … The perineuronal net and the control of CNS plasticity. Cell …

Looking inside the matrix: perineuronal nets in plasticity, maladaptive plasticity and neurological disorders

C De Luca, M Papa - Neurochemical Research, 2016 - Springer
plasticity and neuronal death. Perineuronal nets (PNNs) in the extracellular matrix (ECM)
provide synaptic integration and control the functional wiring between neurons. These …

Cerebellar plasticity and associative memories are controlled by perineuronal nets

D Carulli, R Broersen, F de Winter… - Proceedings of the …, 2020 - National Acad Sciences
Perineuronal nets (PNNs) are assemblies of … plasticity. PNNs are prominently expressed
around neurons of the deep cerebellar nuclei (DCN), but their role in adult cerebellar plasticity

Perineuronal nets gain prominence for their role in learning, memory, and plasticity

HH Shen - Proceedings of the National Academy of …, 2018 - National Acad Sciences
… of perineuronal nets … for plasticity,” says neuroscientist Takao Hensch at Harvard University.
Building on that study, other researchers discovered that perineuronal nets regulate plasticity