… In conclusion, recent discoveries show that PNN formation contributes to a loss of brain
plasticity in adults, and that brain and spinal cord plasticity can be reestablished in adults after …

… plasticity was previously reviewed [19], and in this paper we will focus on the role of ECM in
neural plasticity. … ECM develops into a specific formation termed perineuronal nets [20, 21]. …

… The relationship between neurons and perineuronal nets (PNNs) is attracting attention
as a central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …

… Perineuronal nets (PNNs) are reticular structures that … The involvement of PNNs in neuronal
plasticity has been … on their unique roles in neuronal development and plasticity. The PNN is …

Abstract: Perineuronal nets (PNNs) are reticular structures resulting from the aggregation of …
late in neural development, inversely correlating with the level of neural plasticity. PNNs …

… is remarkably dynamic, changing its plasticity-associated conditions, including … perineuronal
nets contribute to the maturation of brain circuits and the regulation of adult brain plasticity …

… Researchers still have a lot of questions about how perineuronal nets form, how they … neural
plasticity. But many intriguing clues have emerged. In many brain regions, perineuronal nets …

… axon regeneration and neural plasticity in the … Neural plasticity can also be guided by
environmental stimuli and rehabilitation, in particular, while ChABC enhances synaptic plasticity…

… Here, we present evidence that perineuronal nets (PNNs), a specialized extracellular …
plasticity-resistant excitatory CA2 synapses; thus, PNNs play a role in restricting synaptic plasticity …

Rapidly emerging evidence implicates perineuronal nets (PNNs) and extracellular matrix (ECM)
molecules that compose or interact with PNNs, in the pathophysiology of several …