… the “loose” ECM, which is present throughout the brain and spinal cord; (2) the membrane-…
brain and spinal cord called perineuronal nets (PNNs), which tightly interdigitate with synaptic …

… The ECM has emerged as an important participant in synaptic plasticity, and in particular
the structures comprised of condensed ECM known as perineuronal nets (PNNs); [ …

… synapse formation and plasticity was previously reviewed [19], and in this paper we will focus
on the role of ECM in neural plasticity. … specific formation termed perineuronal nets [20, 21]. …

… emphasis on loss of perineuronal nets (PNNs) in several brain regions in this disorder.
We then briefly review evidence for a significant involvement of synaptic pathology in this …

… Perineuronal nets (PNNs) are reticular structures that surround the cell body of many
neurones, and extend along their dendrites. They are considered to be a specialized extracellular …

The perineuronal net (PNN) represents a lattice‐like structure that is prominently expressed
along the soma and proximal dendrites of parvalbumin‐ (PV‐) positive interneurons in …

… implicated in promoting synaptic plasticity, perineuronal nets (PNNs… plasticity (Dityatev et
al., 2010). We previously identified hippocampal area CA2 as a region where synaptic plasticity …

… are released by neurons and glial cells form perineuronal nets (PNNs) and modulate many
… as the participation of PNNs in synaptic plasticity and some clinical aspects of perineuronal …

… is remarkably dynamic, changing its plasticity-associated conditions, including … perineuronal
nets contribute to the maturation of brain circuits and the regulation of adult brain plasticity …

Abstract: Perineuronal nets (PNNs) are reticular structures resulting from the aggregation of …
late in neural development, inversely correlating with the level of neural plasticity. PNNs …