Mouse hematopoietic cell–targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype
C Mantel, S Messina-Graham, A Moh… - Blood, The Journal …, 2012 - ashpublications.org
… −/− animals is lengthened by treatment with a reactive oxygen species scavenger, which …
Reactive oxygen species (ROS) can activate the JAK/STAT pathway. JAKs are nonreceptor …
Reactive oxygen species (ROS) can activate the JAK/STAT pathway. JAKs are nonreceptor …
[图书][B] Autoinflammation in the TNF Receptor-Associated Periodic Syndrome (TRAPS): Pathophysiology and Implications for Treatment
AC Bulua - 2011 - search.proquest.com
… Mitochondrial reactive oxygen species promote production of pro]inflammatory cytokines
and are elevated in TNFR1]Associated Periodic Syndrome (TRAPS). J Exp Med, 2011. 208 (3): …
and are elevated in TNFR1]Associated Periodic Syndrome (TRAPS). J Exp Med, 2011. 208 (3): …
[HTML][HTML] Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome
J Dudek, IF Cheng, M Balleininger, FM Vaz… - Stem cell …, 2013 - Elsevier
… on mitochondrial oxidative phosphorylation. We found an impaired remodeling of cardiolipin,
a dramatic decrease in basal oxygen … in generation of reactive oxygen species. Our data …
a dramatic decrease in basal oxygen … in generation of reactive oxygen species. Our data …
Mitochondrial dysfunction increases allergic airway inflammation
L Aguilera-Aguirre, A Bacsi… - The Journal of …, 2009 - journals.aai.org
… reactive oxygen species (ROS) and induce mitochondrial dysfunction in the airway epithelium.
In this study, we investigated the involvement of preexisting mitochondrial … mitochondrial …
In this study, we investigated the involvement of preexisting mitochondrial … mitochondrial …
Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis augment non-surgical bleeding in heart failure patients supported by continuous …
NK Mondal, EN Sorensen, NJ Hiivala, ED Feller… - Platelets, 2015 - Taylor & Francis
… The aim of this study was to examine the role of intraplatelet reactive oxygen species (ROS)
and platelet damage on the incidence of bleeding events after CF-LVAD implantation in HF …
and platelet damage on the incidence of bleeding events after CF-LVAD implantation in HF …
Systemic and cellular responses to intermittent hypoxia: evidence for oxidative stress and mitochondrial dysfunction
Episodic hypoxia is associated with recurrent apnea syndromes (central or obstructive
apneas). Epidemiological studies have shown good correlation between apneas and …
apneas). Epidemiological studies have shown good correlation between apneas and …
Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia
… However, it remains unknown which reactive oxygen species (ROS) are responsible for
this activation of NLRP3 inflammasomes and how such action of ROS is controlled. This study …
this activation of NLRP3 inflammasomes and how such action of ROS is controlled. This study …
[HTML][HTML] Reactive oxygen species in macrophages: sources and targets
M Canton, R Sánchez-Rodríguez, I Spera… - Frontiers in …, 2021 - frontiersin.org
Reactive oxygen species (ROS) are fundamental for … However, growing evidence highlights
mitochondria as a crucial … of mitochondrial as compared to non-mitochondrial ROS sources. …
mitochondria as a crucial … of mitochondrial as compared to non-mitochondrial ROS sources. …
[HTML][HTML] Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure?
… Besides ATP synthesis, the best-known function of mitochondria, they are involved in … most
important mitochondrial activities are oxidative phosphorylation and reactive oxygen species (…
important mitochondrial activities are oxidative phosphorylation and reactive oxygen species (…
Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome
S Tsuji, H Matsuzaki, M Iseki, A Nagasu… - Clinical & …, 2019 - academic.oup.com
… Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is an … and
T90I mutations showed increased mitochondrial reactive oxygen species (ROS). Furthermore, …
T90I mutations showed increased mitochondrial reactive oxygen species (ROS). Furthermore, …