… analgesic effect of dibutyryl cyclic GMP or acetylcholine (ACh) injected into rat paws. Since
ACh induces nitric oxide … GMP pathway in ACh-induced analgesia, using a modification of the …

… Analgesia by direct antagonism of nociceptor sensitization invohles the arginine-nitric oxide-…
peripheral analgesia by release of nitric oxide. In Moncada S, Higgs EA (Eds) 'Nitric oxide …

… This review summarizes basic concepts of inflammatory pain that are necessary to understand
the mechanisms of peripheral NO signaling that promote peripheral analgesia; we also …

… the periphery, acetylcholine-induced analgesia was mediated via the activation of the nitric
oxide/… which nonenzymatically releases nitric oxide (NO), caused analgesia. Furthermore, the …

… In addition to data showing that nitric oxide donor induces peripheral antinociception, the
role of NO in pain control was also shown at central levels. l-Arginine and the …

… to investigate the role of the nitric oxide–cyclic GMP pathway in various … peripheral
antinociception. In addition, sodium nitroprusside and l-arginine increased the sildenafil analgesia …

… We recently discovered that the local peripheral analgesic effect of dipyrone could be
abolished by pretreating of the paws with L-NMMA, a nitric oxide synthase inhibitor, or …

… In our model of chronic neuropathic pain in rats, induced by lesion or ligation of peripheral …
NOS inhibitors provide analgesia. Our group demonstrated that a peripheral nerve lesion in a …

… We tested the hypothesis that activation of the nitric oxide (NO)-cGMP pathway is involved
in the mechanism of two directly acting non-opiate peripheral analgesics, myrcene and …

… Here, we show that the peripheral antinociceptive effect of morphine is lost in neuronal
nitric-oxide synthase null mice and that morphine induces the production of nitric oxide in primary …