Functional domain mapping of peroxin Pex19p: interaction with Pex3p is essential for function and translocation
Y Matsuzono, T Matsuzaki, Y Fujiki - Journal of cell science, 2006 - journals.biologists.com
… The peroxin Pex19p functions in peroxisomal membrane assembly. Here we mapped
functional domains of human Pex19p comprising 299 amino acids. Pex19p mutants deleted in the …
functional domains of human Pex19p comprising 299 amino acids. Pex19p mutants deleted in the …
Functional regions of the peroxin Pex19 necessary for peroxisome biogenesis
… Pex19 plays multiple roles in these processes, but how these functions relate to the … of
the Pex19 domains is unresolved. To this end, using deletion mutants, we mapped the Pex19 …
the Pex19 domains is unresolved. To this end, using deletion mutants, we mapped the Pex19 …
Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10
DA Hadden, BA Phillipson, KA Johnston… - Molecular membrane …, 2006 - Taylor & Francis
… Peroxisomes import integral membrane proteins post-translationally, and PEX19 is a …
We report the characterisation of the Arabidopsis thaliana homologue of PEX19 which is a …
We report the characterisation of the Arabidopsis thaliana homologue of PEX19 which is a …
Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p
Y Sato, H Shibata, T Nakatsu, H Nakano… - The EMBO …, 2010 - embopress.org
… require peroxin … Pex19p with its docking protein Pex3p at the peroxisomal membrane. This
study presents the crystal structure of the cytosolic domain of Pex3p in complex with a Pex19p …
study presents the crystal structure of the cytosolic domain of Pex3p in complex with a Pex19p …
Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19
F Schmidt, N Treiber, G Zocher, S Bjelic… - Journal of biological …, 2010 - ASBMB
… The human peroxins PEX3 and PEX19 play a central role in … as the receptor for cytosolic
PEX19, which in turn recognizes … of the cytosolic domain of PEX3 in complex with a PEX19-…
PEX19, which in turn recognizes … of the cytosolic domain of PEX3 in complex with a PEX19-…
Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis
M Fransen, I Vastiau, C Brees, V Brys… - Journal of molecular …, 2005 - Elsevier
… Alternatively, Pex19p might act as a multifunctional peroxin and participate in a number
of these activities. Here, we have employed transposon mutagenesis to generate a library of …
of these activities. Here, we have employed transposon mutagenesis to generate a library of …
Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals
FJ Vizeacoumar, WN Vreden, JD Aitchison… - Journal of Biological …, 2006 - ASBMB
… The peroxin Pex19p has been proposed to be either the receptor … Pex19p could be achieved
by determining whether the peroxisomal targeting signal (PTS) and the region of Pex19p …
by determining whether the peroxisomal targeting signal (PTS) and the region of Pex19p …
[HTML][HTML] Import of peroxisomal membrane proteins: the interplay of Pex3p-and Pex19p-mediated interactions
Y Fujiki, Y Matsuzono, T Matsuzaki… - Biochimica et Biophysica …, 2006 - Elsevier
… homologues of known yeast peroxins, and the corresponding … and Pex19p – two evolutionarily
conserved peroxins – in … terminal domain of Pex19p by which the function of the peroxin …
conserved peroxins – in … terminal domain of Pex19p by which the function of the peroxin …
The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis
K Ghaedi, S Tamura, K Okumoto… - Molecular biology of …, 2000 - Am Soc Cell Biol
… Accordingly, Pex16p and Pex19p can also be categorized into this group of peroxins. We
demonstrated in the present study that the membrane assembly process(es) involving …
demonstrated in the present study that the membrane assembly process(es) involving …
Identification and characterization of the human peroxin PEX3
M Soukupova, C Sprenger, K Gorgas… - European journal of cell …, 1999 - Elsevier
… map regions of PEX3 which would interact with PEX19 we … when PEX19 was fused behind
the GAL4-binding domain. Two … the truncated PEX3 protein and PEX19 could mean that the …
the GAL4-binding domain. Two … the truncated PEX3 protein and PEX19 could mean that the …