The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis

K Ghaedi, S Tamura, K Okumoto… - Molecular biology of …, 2000 - Am Soc Cell Biol
… Accordingly, Pex16p and Pex19p can also be categorized into this group of peroxins. We
demonstrated in the present study that the membrane assembly process(es) involving …

Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p

JR Su, K Takeda, S Tamura… - Proceedings of the …, 2009 - National Acad Sciences
domain mediates dynamic interactions with other peroxins including Pex5p, Pex13p, and …
with other peroxins such as Pex5p, Pex13p, and Pex19p are mediated by the domain (15, …

Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains

B Schrul, RR Kopito - Nature cell biology, 2016 - nature.com
… In this study we identified PEX19 and BAG6 as direct HP-domain-specific binding partners
of newly synthesized UBXD8 and provide three lines of evidence supporting the conclusion …

Conservation of PEX19-binding motifs required for protein targeting to mammalian peroxisomal and trypanosome glycosomal membranes

T Saveria, A Halbach, R Erdmann… - Eukaryotic …, 2007 - Am Soc Microbiol
… membrane proteins which require the peroxin PEX19 for insertion into the peroxisomal …
brucei PEX19 is very similar to those previously identified for human and yeast PEX19. Our …

Peroxisome function relies on organelle-associated mRNA translation

N Dahan, YS Bykov, EA Boydston, A Fadel, Z Gazi… - Science …, 2022 - science.org
… Because Pex14 contains a Pex19 binding domain at its N terminus (7), the most trivial …
of Pex19 was visualized in strains that were previously described in which these peroxins are …

Peroxin 5: A cycling receptor for protein translocation into peroxisomes

CP Williams, WA Stanley - The international journal of biochemistry & cell …, 2010 - Elsevier
Peroxins are proteins that regulate the biogenesis of peroxisomes—small vesicular … A key
peroxin – to date the best studied – is peroxin 5. Structurally, peroxin 5 is a bi-domain protein …

Peroxisome biogenesis

PE Purdue, PB Lazarow - Annual review of cell and …, 2001 - annualreviews.org
… Consistent with these dual roles, in wild-typecells, some of the PpPex17p is bound to the
docking complex and some iscomplexed with Pex19p (the mostly cytosolic peroxin that is …

The Leishmania donovani peroxin 14 binding domain accommodates a high degeneracy in the pentapeptide motifs present on peroxin 5

H Hojjat, A Jardim - Biochimica et Biophysica Acta (BBA)-General Subjects, 2015 - Elsevier
… Deletion mutagenesis, pull-down, and bacterial two hybrid assay were used to map the
LdPEX5 domain bound by LdPEX14. ELISA assays, ITC, intrinsic fluorescence and size …

Insights into the structure and function of the Pex1/Pex6 AAA-ATPase in peroxisome homeostasis

RM Judy, CJ Sheedy, BM Gardner - Cells, 2022 - mdpi.com
domains that serves as a recognition site for the cytosolic PMP receptor, Pex19 [35,36]. …
domain to the C-terminus is important for binding to Pex19 and peroxisome targeting [198]. …

Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p–Pex21p

D Pan, T Nakatsu, H Kato - Nature structural & molecular biology, 2013 - nature.com
… Pex7p together with a co-receptor peroxin. Crystal structures of the PTS1-binding domain of
… of Pex7p or the PTS2-interaction domain of the co-receptor peroxin, ligated with or without …