The interaction between human PEX3 and PEX19 characterized by fluorescence resonance energy transfer (FRET) analysis

AC Muntau, AA Roscher, WH Kunau, G Dodt - European journal of cell …, 2003 - Elsevier
… Among the corresponding peroxins the interaction between PEX3 and PEX19 is essential
for early peroxisome biogenesis. However, the intracellular site of this protein interaction is still …

Peroxisome biogenesis and human peroxisome-deficiency disorders

Y Fujiki - Proceedings of the Japan Academy, Series B, 2016 - jstage.jst.go.jp
… Defects of PEX3, PEX16 and PEX19 encoding membrane-assembly peroxins lead to absence
of ghosts and cause ZS phenotypes. Many cell lines from milder PBD patients, those with …

A dual role of the conserved PEX19 helix in safeguarding peroxisomal membrane proteins

J Oh, DK Kim, SH Ahn, HM Kim, H Cho - Iscience, 2024 - cell.com
PEX19 helix, αd, is critical to prevent improper exposure of the PEX26 transmembrane domain
(… find that the cytosolic domain of PEX3 interacts with the αd helix of PEX19, a secondary …

[HTML][HTML] Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins

EH Hettema, W Girzalsky, M van den Berg… - The EMBO …, 2000 - embopress.org
… Combined with these data, we now have evidence for the essential role of three peroxins in
PMP localization: Pex3p, Pex19p and Pex16p. Pex19p has been identified in both yeast and …

[HTML][HTML] Human disorders of peroxisome metabolism and biogenesis

HR Waterham, S Ferdinandusse… - Biochimica Et Biophysica …, 2016 - Elsevier
… There are 3 peroxins recognized with a specific function in the biogenesis of peroxisomal
membranes: PEX3, PEX16 and PEX19 (Fig. 2). PEX19 is a mainly cytosolic protein that is …

[HTML][HTML] Mammalian Pex14p: membrane topology and characterisation of the Pex14p–Pex14p interaction

MEM Oliveira, C Reguenga, AMM Gouveia… - … et Biophysica Acta (BBA …, 2002 - Elsevier
… Besides refining the membrane topology model of this peroxin, we … Domain mapping of the
Pex14p–Pex14p interaction … Two peroxins, Pex5p and Pex19p, have been shown to bind to …

[PDF][PDF] Molecular characterization of the Pex19p-Pex3p and Pex19p-Pex16p interactions

IJ Broekaert - 2003 - d-nb.info
… mammalian pex mutants, three peroxins (Pex3p, Pex16p, Pex19p) have been shown to be
required for insertion of PMPs. These membrane-associated peroxins might be involved in …

Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX proteins

RLM Jansen, C Santana-Molina… - Frontiers in cell and …, 2021 - frontiersin.org
… , PEX19 and PEX16. PMPs can sort directly to peroxisomes or indirectly via the ER. In the
direct pathway PEX19 … The Pex11 protein family (all show as PEX11) and the fungal peroxins

[HTML][HTML] … into the distribution, protein abundance and subcellular localisation of the endogenous peroxisomal biogenesis proteins PEX3 and PEX19 in different organs …

C Colasante, J Chen, B Ahlemeyer, R Bonilla-Martinez… - PloS one, 2017 - journals.plos.org
… To investigate the organ- and cell type-specific distribution of the peroxins PEX3 and PEX19
we used immunofluorescence stainings on formalin-fixed paraffin-embedded organ sections…

Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p …

H Otera, K Setoguchi, M Hamasaki… - … and cellular biology, 2002 - Taylor & Francis
… of the respective peroxins as well as of a whole complex. … by at least three peroxins,
Pex3p, Pex16p, and Pex19p, and the … Domain mapping of Pex13p involved in interaction with …