… the therapeutic potential of autophagy modulators, analyse the obstacles that have limited
their development and propose strategies that may unlock the full therapeutic potential of …

… by several factors including inadequate tumor infiltration and persistence/activation in the
tumor … potential strategies to circumvent such obstacles towards superior therapeutic activity. …

… data demonstrating the vast therapeutic potential of NAS-targeting molecules, identify the
obstacles preventing the complete realization of such potential and formulate strategies to …

… therapeutic potential of targeting mitochondria in patients with cardiovascular disease,
examine the obstacles … strategies that might empower the full clinical potential of this approach. …

… potential to the clinic have been disappointing, largely due to significant delivery obstacles.
… of this class of molecules persisted? The unique features of neurotrophic factors and the …

… Although proof of principle has been provided that implanted chondrocytes can contribute
to structural cartilage repair, the origin of cells persisting at the repair site, whether these are …

During highly active antiretroviral therapy (HAART), HIV-1 can still persist in circulating,
resting CD4 + T lymphocytes, lymph node mononuclear cells, and seminal cells of patients …

… persisted in a subsequent 52-week follow-up (~56% in treated group versus ~38% in placebo
group), demonstrating the potential of … to fully unleash the therapeutic potential of MSCs. …

… allowing for the prolonged survival and persistence of the bacilli [5]… persisting bacilli. Much
research effort focuses on understanding the biology of persistence and developing therapies …

… One group of ideal target cells for retrovirus vectors consists of so-called stem cells, which
persist indefinitely and also produce more specialized descendant cells. Blood-forming stem …