3 天前 - … The first obstacle is the existence of a considerable black figure in prison, both at the
… The second difficulty encountered is the persistence of very limited intervention resources, …

5 天前 - … However, obstacles to the practical application of defensins as anti-infective
therapies persist due to the unique properties of human β-defensins themselves and serious …

6 天前 - … Chimeric Antigen Receptor T-cell (CAR-T) therapies are transforming the treatment
of B-… for their implementation persist. Global access disparities persist, particularly for …

12 天前 - … its therapeutic applications. However, despite these potential benefits, challenges
persist, such as limited bioavailability and technological obstacles hindering its large-scale …

12 天前 - … One major obstacle is the lack of unique tumor-associated … Moreover, CAR-T cells
often struggle with persistence and … the therapeutic potential of CAR-T cell therapy for solid …

17 天前 - … (i) to identify current obstacles impeding … persisting immunosuppression phase.
This time-varying host response urges to develop time-resolved test to characterize persistence …

19 天前 - … Nevertheless, despite remarkable achievements, considerable challenges persist.
… the solid tumours, present formidable obstacles. Researchers have proposed strategies that …

25 天前 - … Chemotherapy persists as the primary intervention for breast cancer, with
chemoresistance posing the principal obstacle to successful treatment. Herein, we show that …

41 天前 - … small and large molecules and gene therapies. Despite the exciting progress,
obstacles such as regulatory barriers, scalability, and long-term biocompatibility persist. It will be …

43 天前 - … vectors, face obstacles such as potential immunogenicity, … -term expression stability
persist. The review underscores … the full therapeutic potential of this cutting-edge domain. …