The prospects for “personalized medicine” in drug development and drug therapy

J Woodcock - Clinical Pharmacology & Therapeutics, 2007 - Wiley Online Library
… : medicine is still more an art than a science. The last 30 years brought an explosion of
therapeutic options … “Personalized medicine” represents the hope that the next decade will bring a …

[HTML][HTML] Personalized medicine: recent progress in cancer therapy

V Gambardella, N Tarazona, JM Cejalvo, P Lombardi… - Cancers, 2020 - mdpi.com
… to drug therapy [33]. Metabolomics can also help in evaluating drug resistance and disease
relapse [34,35], leading to opportunities for the development of novel therapeutic strategies […

Drug therapy and personalized health care: pharmacogenomics in perspective

W Sadee - Pharmaceutical research, 2008 - Springer
… and gene therapy strategies … drug therapy for each patient could significantly improve
treatment outcomes, even with existing drugs, in the re-emerging era of personalized medicine. As …

Personalized vascular medicine: individualizing drug therapy

EM Degoma, G Rivera, SM Lilly… - … Medicine, 2011 - journals.sagepub.com
Personalized medicine refers to the application … therapeutic management. The appealing
concept of individualized care is not novel, but rather has stood as a central tenet of medicine

Targeted therapy and personalized medicine in hepatocellular carcinoma: drug resistance, mechanisms, and treatment strategies

D Galun, T Srdic-Rajic, A Bogdanovic… - Journal of …, 2017 - Taylor & Francis
Hepatocellular carcinoma (HCC) is characterized by a growing number of new cases diagnosed
each year that is nearly equal to the number of deaths from this cancer. In a majority of …

Pharmacogenomics: the promise of personalized medicine

L Mancinelli, M Cronin, W Sadée - Aaps Pharmsci, 2000 - Springer
drug discovery, an individualized application of drug therapy, and new insights into disease
prevention. Current concepts in drug therapy … -based differences in drug response. In contrast…

Personalized medicine: revolutionizing drug discovery and patient care

GS Ginsburg, JJ McCarthy - TRENDS in Biotechnology, 2001 - cell.com
… The personalized medicine strategy for drug discovery and development … drug therapy to
those patients who will have an optimal response. The business rationale for targeted therapies

[HTML][HTML] Personalized medicine and the practice of medicine in the 21st century

AM Issa - McGill Journal of Medicine: MJM, 2007 - ncbi.nlm.nih.gov
… adverse drug reactions by identifying poor metabolizers at the initiation of drug therapy. The
… metabolizers prior to the initiation of drug therapy is an appealing emerging opportunity for …

Nanotheranostics for personalized medicine

S Mura, P Couvreur - Advanced drug delivery reviews, 2012 - Elsevier
… This approach offers the advantages to improve drug therapeutic efficiency and to dramatically
reduce toxicity and unspecific side effects, thus leading to possible future evolution in the …

[PDF][PDF] Realizing the promise of personalized medicine

MG Aspinall, RG Hamermesh - Harvard business review, 2007 - lbnc.epfl.ch
drug therapy accordingly. Down the road, one particularly promising area is cardiovascular
disease. Researchers are making strides toward identifying genetic variants in patients who …