… This trial reiterates the importance of incorporating prospective molecular profiling into the
selection criteria for early-phase clinical trials examining targeted therapies. These dramatic …

… An understanding of the molecular technologies that profile DNA, RNA, protein, and metabolites
will be essential for physicians to make personalized medicine a reality. Profiling of DNA…

… A complete molecular profiling of tumor DNA can be performed with high throughput genotyping
and/or next generation sequencing platforms. The identification of predictive biomarkers …

… personalized anti-tumoral therapies. We explored the feasibility, efficacy, and the impact of
molecular profiling … treatment, and for whom molecular profiles had been achieved using next-…

… Here, we summarize key molecular, biological, and technical criteria that, in our view, … tumor
molecular profiling for PM trials. Precision medicine (PM), also called “personalized medicine…

… approaches to implement precision cancer medicine, highlighting the challenges and …
utility of molecular profiling results. We describe novel molecular characterization strategies …

… molecular profiling relevant to a wide range of research topics. … by molecular profiling of
biopsy tissue is conventionally conducted by immunohistochemistry and bulk genomic profiling […

… determine if tumor collection, prospective molecular profiling, and PMed report generation …
profiling. A subsequent bioinformatics workflow transformed genomic data into a personalized …

… A comprehensive evaluation of a tumor’s molecular profile requires the integration of
genomic data at multiple levels. As a proof of concept, we used an integrative approach to show …

… profiling demonstrated that breast cancer is a heterogeneous disease at the molecular level
and that molecular profiling … corroborated when considering molecular profiles other than …