Differentiated thyroid cancerpersonalized therapies to prevent overtreatment

M Luster, T Weber, FA Verburg - Nature Reviews Endocrinology, 2014 - nature.com
… I ablation in only a minority of patients with thyroid cancer, a 2013 survey reported the use of
… of individualized therapies. In this Review, we discuss the personalized therapies for DTC …

Personalized therapy in patients with anaplastic thyroid cancer: targeting genetic and epigenetic alterations

N Smith, C Nucera - The Journal of Clinical Endocrinology & …, 2015 - academic.oup.com
… of thyroid cancer and, more importantly, could be related to their molecular profile (ie, genetic
and epigenetic alterations) (42, 48), likely because in differentiated thyroid cancers we do …

Personalized treatment options for thyroid cancer: current perspectives

F Khatami, B Larijani, S Nikfar… - … and personalized …, 2019 - Taylor & Francis
… More than that, some studies identified several genetic alterations as the vital determinant
or for the development of personalized therapies for thyroid cancer. By way of illustration, the …

[HTML][HTML] Differentiated thyroid cancer, from active surveillance to advanced therapy: toward a personalized medicine

A Matrone, MC Campopiano, A Nervo… - Frontiers in …, 2020 - frontiersin.org
thyroid cancer (DTC) showed the need of a personalized management approach.
Despite the increased diagnosis of DTC, in particular small papillary thyroid cancers, cancer-related …

Personalization of targeted therapy in advanced thyroid cancer

P Fallahi, S Martina Ferrari, V Mazzi, R Vita… - Current …, 2014 - ingentaconnect.com
… to a new era of patient-specific and personalized care. Recently, key targets that are now …
thyroid cancer include B-Raf gene mutations, rearranged during transfection/ papillary thyroid

Primary cell cultures for the personalized therapy in aggressive thyroid cancer of follicular origin

P Fallahi, SM Ferrari, G Elia, F Ragusa… - Seminars in Cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignancy. More than 90 % of TC is
represented by differentiated TC (DTC) arising from the follicular thyroid cells. DTC includes …

[HTML][HTML] New therapies for advanced thyroid cancer

D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer … of thyroid cancer, thus allowing more personalized treatments for patients with …

Thyroid cancer: risk-stratified management and individualized therapy

F Raue, K Frank-Raue - Clinical Cancer Research, 2016 - AACR
… The clinician and patient should discuss expectations regarding quality of life, and the
risks and benefits of therapy to determine the best personalized treatment plan. The treatment …

Navigating systemic therapy in advanced thyroid carcinoma: from standard of care to personalized therapy and beyond

SN Rao, ME Cabanillas - Journal of the Endocrine Society, 2018 - academic.oup.com
… Schematic of the two commonly activated pathways and genetic aberrations involved in
thyroid cancer, as well as the targeted therapies studied in thyroid cancer. The MAPK and the …

[HTML][HTML] Artificial intelligence for personalized medicine in thyroid cancer: current status and future perspectives

LR Li, B Du, HQ Liu, C Chen - Frontiers in Oncology, 2021 - frontiersin.org
Thyroid cancers (TC) have increasingly been detected … step toward the goal of personalized
medicine. The diagnosis of … with several challenges regarding personalized care in TC, for …