Epigenetics in Alzheimer's disease: perspective of DNA methylation

TJ Qazi, Z Quan, A Mir, H Qing - Molecular Neurobiology, 2018 - Springer
… (FAD), and autosomal dominant Alzheimer’s disease (ADAD). Down to the minutest of …
methylation patterns like mitochondrial DNA methylation and ribosomal DNA (rDNA) methylation. …

DNA methylation in the pathology of Alzheimer's disease: from gene to cognition

CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… is a growing field that provides a new perspective on the physiological and behavioral
changes caused by this neurodegenerative disorder. Given that APP/Aβ is known to modulate the …

Dynamics of DNA methylation in aging and Alzheimer's disease

HA Irier, P Jin - DNA and cell biology, 2012 - liebertpub.com
… of DNA methylation in neurodegenerative diseases, with a special focus on DNA methylation
dynamics … : from prevention to therapeutic perspectives. J Am Med Dir Assoc 9, 390–405. …

DNA methylation and Alzheimer's disease

T van Groen - Epigenetics of aging, 2010 - Springer
… In conclusion, epigenetics plays a direct and indirect role in the chances of developing
Alzheimer’s disease; the decreased DNA methylation status with increasing age of the APP, PS1, …

Prediction of Alzheimer's disease based on deep neural network by integrating gene expression and DNA methylation dataset

C Park, J Ha, S Park - Expert Systems with Applications, 2020 - Elsevier
approach was better than that of DNA methylationapproach performed better than the case
where we used PCA or t-SNE in each dataset, including gene expression, DNA methylation

Association of blood-based DNA methylation markers with late-onset Alzheimer disease: a potential diagnostic approach

B Acha, J Corroza, J Sánchez-Ruiz de Gordoa… - Neurology, 2023 - AAN Enterprises
… to identify novel noninvasive biomarkers for Alzheimer disease (AD) diagnosis. Recent …
DNA methylation marker panel as a noninvasive tool to identify patients with late-onset Alzheimer

[PDF][PDF] Perspectives in genetic prediction of Alzheimer's disease

O Šerý, J Povová, VJ Balcar - Neuroendocrinol Lett, 2014 - nel.edu
… testing for both Alzheimer diseases and other multifactorial disorders. An interesting and …
Paternal stress prior to conception alters DNA methylation and behaviour of developing rat …

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease

L Zhang, TC Silva, JI Young, L Gomez… - Nature …, 2020 - nature.com
… utility of DNA methylation as clinical biomarkers, we also compared methylation differences
in … In the coMethDMR approach, we tested 40,010 pre-defined genomic regions to identify co-…

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

…, Alzheimer's Disease Neuroimaging Initiative (ADNI) - Clinical …, 2020 - Springer
… in DNA methylation that associate with disease progression. … disease is critically important
and can change our approach … funded by the Alzheimer's Disease Neuroimaging Initiative (…

[PDF][PDF] DNA methylation alterations in Alzheimer's disease

AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
… the association between DNA methylation alterations and AD. Global DNA methylation
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. …