The role of iron metabolism, lipid metabolism, and redox homeostasis in Alzheimer's disease: from the perspective of ferroptosis

L Wu, X Xian, Z Tan, F Dong, G Xu, M Zhang… - Molecular …, 2023 - Springer
… potential role of ferroptosis in AD, the involvement of ferroptosis in the pathological … ferroptosis
for AD. Intervention strategies based on ferroptosis are promising for Alzheimer’s disease

Revisiting the intersection of microglial activation and neuroinflammation in Alzheimer's disease from the perspective of ferroptosis

M Wang, G Tang, C Zhou, H Guo, Z Hu, Q Hu… - Chemico-Biological …, 2023 - Elsevier
… In this case, disturbances in brain iron homeostasis and neuronal ferroptosisferroptosis,
microglia, AD, and their relationship. Second, we discuss the nonnegligible role of ferroptosis in …

[HTML][HTML] The potential of ferroptosis-targeting therapies for Alzheimer's disease: From mechanism to transcriptomic analysis

N Majerníková, WFA den Dunnen… - Frontiers in Aging …, 2021 - frontiersin.org
… in ferroptosis, we discuss how these processes relate to AD, and we analyze which
ferroptosis-related genes are differentially expressed in AD brain dependant on cell type, disease

The potential role of ferroptosis in Alzheimer's disease

G Zhang, Y Zhang, Y Shen, Y Wang… - … Alzheimer's Disease, 2021 - content.iospress.com
… Mounting evidence suggests that ferroptosis may be involved in neurological disorders, …
mechanisms of ferroptosis; discuss the potential interaction between AD and ferroptosis in terms …

[HTML][HTML] Mechanisms of ferroptosis in Alzheimer's disease and therapeutic effects of natural plant products: a review

D Zhao, K Yang, H Guo, J Zeng, S Wang, H Xu… - Biomedicine & …, 2023 - Elsevier
… targeting the ferroptosis process, this review summarizes the research progress on the
mechanism of ferroptosis in AD and the natural plant products that regulate ferroptosis in AD. …

Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective

PJ Derry, ML Hegde, GR Jackson, R Kayed… - Progress in …, 2020 - Elsevier
The complexity of Alzheimer’s disease (AD) complicates the search for effective treatments.
While the key roles of pathologically modified proteins has occupied a central role in …

[HTML][HTML] Iron metabolism, ferroptosis, and the links with Alzheimer's disease

N Yan, JJ Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
… These studies provide us novel perspectives. Hence, we summarize the current knowledge
of iron metabolism and ferroptosis, and review the contributions of iron and ferroptosis to AD. …

Preventive and therapeutic strategies in Alzheimer's disease: focus on oxidative stress, redox metals, and ferroptosis

G Plascencia-Villa, G Perry - Antioxidants & redox signaling, 2021 - liebertpub.com
… Misregulated ferroptosis pathways have been speculated to … designed as ferroptosis inductors
or ferroptosis inhibitors. … as a critical component of ferroptosis, because GPX4 functions as …

[HTML][HTML] A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's Disease

L Zhang, J Fang, Z Tang, Y Luo - International Journal of Medical …, 2022 - ncbi.nlm.nih.gov
… Our results demonstrated that the expression of several ferroptosis-related genes is …
that ferroptosis plays an essential role in AD pathogenesis and that inhibiting ferroptosis

[HTML][HTML] The mechanisms of ferroptosis and its role in alzheimer's disease

H Ma, Y Dong, Y Chu, Y Guo, L Li - Frontiers in Molecular …, 2022 - frontiersin.org
… The ferroptosis pathways within nerve cells include iron homeostasis regulation, cystine/…
to ferroptosis. This review explores the connection between AD and the ferroptosis signaling …