Targeting to macrophages: role of physicochemical properties of particulate carriers—liposomes and microspheres—on the phagocytosis by macrophages

F Ahsan, IP Rivas, MA Khan, AIT Suárez - Journal of controlled release, 2002 - Elsevier
… materials and activating macrophages with various activating … can also control the process
of phagocytosis. Because of the … particulate carriers on the phagocytosis by macrophages. …

Influence of particle geometry and PEGylation on phagocytosis of particulate carriers

R Mathaes, G Winter, A Besheer, J Engert - International Journal of …, 2014 - Elsevier
… different particles sizes, we found that 150 nm particles did not sediment on macrophages
during … geometry reduces the recognition and phagocytosis by macrophages. The two uptake …

Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome

B Patel, N Gupta, F Ahsan - European Journal of Pharmaceutics and …, 2015 - Elsevier
… the phagocytosis of inhalable particulate drug carriers. Phagocytosis is an active process
for uptake of particles observed in macrophages, monocytes, neutrophils and somewhat in …

Understanding the phagocytosis of particles: the key for rational design of vaccines and therapeutics

S Moreno-Mendieta, D Guillén… - Pharmaceutical …, 2022 - Springer
… by professional and nonprofessional phagocytes and have a … the phagocytosis of particles
intended to be used as carrier or … phagocytes mainly include neutrophils and macrophages (…

PEGylation of model drug carriers enhances phagocytosis by primary human neutrophils

WJ Kelley, CA Fromen, G Lopez-Cazares… - Acta biomaterialia, 2018 - Elsevier
… primary cell phagocytosis focus solely on phagocytosis by macrophages and ignore …
whether neutrophils’ preferential phagocytosis of PEGylated particles remained consistent across …

Role of particle size in phagocytosis of polymeric microspheres

JA Champion, A Walker, S Mitragotri - Pharmaceutical research, 2008 - Springer
… are eventually cleared from the body by phagocytosis, which is one of the body’s innate …
non-indigenous particulate matter (8). Macrophages, the body’s phagocytic cells, bind particles

[HTML][HTML] Phagocytosis dynamics depends on target shape

D Paul, S Achouri, YZ Yoon, J Herre, CE Bryant… - Biophysical journal, 2013 - cell.com
… Less is known about the mechanisms by which phagocytosis of organisms and particles
occurs in response to receptor activation by the many nonopsonic receptors. These include …

Update on macrophage clearance of inhaled micro-and nanoparticles

M Geiser - Journal of aerosol medicine and pulmonary drug …, 2010 - liebertpub.com
… : Phagocytic uptake of inhaled and deposited particles is the … particles that deposit along
the entire respiratory tract, however, are not efficiently phagocytosed by surface macrophages. …

Endocytosis of particle formulations by macrophages and its application to clinical treatment

K Hirota, H Terada - Molecular regulation of endocytosis, 2012 - books.google.com
… In this chapter, features of phagocytosis of particles in terms of particle properties, as well
as … Macrophage cells also recognize drug carrier particles as invaders, and then,“undesirable” …

Mechanisms of phagocytosis in macrophages

A Aderem, DM Underhill - Annual review of immunology, 1999 - annualreviews.org
… Thus, phagocytosis by macrophages is criticalfor the … macrophages and neutrophils have
been referred to asprofessional phagocytes and are very efficient at internalizing particles