… the major components of immunosuppressive therapy, explores the current understanding
of pharmacogenetic differences and reviews the role of these differences in a complex …

… Furthermore, with efficient therapeutic drug monitoring it is … The future of pharmacogenetics
will be in treatment models … on pharmacodynamic parameters, variations in the expression of …

… of inherited DNA variations affecting the inter-… Pharmacogenetic research as well as
acceptability and utilization by the clinicians differ between novel immunosuppressant agents…

… immunosuppressive drugs and tailor maintenance therapy. In this review, we attempt to
provide insight into the evolving field of pharmacogenomics … ranges, as variations outside these …

… A crude example of a pharmacogenetic approach is the use of different drug-dosing
regimens based on ethnic group. Individuals who are genetically of sub-Saharan African origin (…

… of pharmacogenomics in relation to immunosuppressive therapy, what the expectations from
pharmacogenomics are, … The major difference is that pharmacogenetics focuses on genetic …

… pharmacogenetics in clinical practice in order to optimize immunosuppressant therapy. …
However, due to therapeutic drug monitoring, variation of trough levels can be corrected by dose …

… highly recommended for several immunosuppressants and is currently based … different
time intervals to estimate an area under the concentration–time curve (AUC). Pharmacogenetics …

… , whereas the term pharmacogenetics usually is applied for the (much older) field of how
genetic differences influence the variability in patients' responses to drugs. Although both terms …

… to immunosuppressive agents is different, so … variations may play a pivotal role (1). Accordingly,
the identification of specific genetic make-up may be helpful to choose the best treatment …