[HTML][HTML] Can pharmacogenomics make a difference in drug development?

FD Ledley - Nature biotechnology, 1999 - nature.com
… The potential benefits of pharmacogenomics on drug development are profound. Achieving
… of conventional development. With the economics of drug development already constrained …

Pharmacogenomics in pharmacy practice: current perspectives

H Elewa, A Awaisu - Integrated Pharmacy Research and Practice, 2019 - Taylor & Francis
drug development and clinical treatment decisions. Citation3 Drug manufacturers and other
pharmaceutical … that the application of pharmacogenomics in clinical practice has resulted in …

Pharmacogenomics in drug development

L Gustavsson - … and proteomics for clinical discovery and development, 2014 - Springer
… new findings into clinical practice. In current clinical practice, pharmacogenomics is only being
… Processes for implementation of a more efficient use of pharmacogenomics are required …

Application of pharmacogenomics in clinical pharmacology

SM Huang, F Goodsaid, A Rahman… - Toxicology …, 2006 - Taylor & Francis
drug development and when it is to be assimilated into labeling and standards of care
that can be used to “individualize” drug therapy and become one of the pillars of “personalized …

[HTML][HTML] Pharmacogenomics in colorectal cancer: Current role in clinical practice and future perspectives

F Battaglin, A Puccini, M Naseem… - Journal of cancer …, 2018 - ncbi.nlm.nih.gov
pharmacogenomic biomarkers validated in clinical practice and future perspectives of
pharmacogenomics … assist in experimental design for drug discovery and disease treatment [196] . …

[HTML][HTML] Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers …

JAG Agúndez, F Abad-Santos, A Aldea… - Frontiers in …, 2012 - frontiersin.org
… /drug pairs in the Spanish study with that of the same pairs in the American Society for Clinical
… and areas of focus to develop a guide for clinical practice in pharmacogenomics testing. …

[HTML][HTML] Opportunities and challenges of implementing pharmacogenomics in cancer drug development

P Tarantino, D Trapani, S Morganti… - Cancer Drug …, 2019 - ncbi.nlm.nih.gov
… and improve clinical trials, as well as clinical practice. The scale is meant in a plastic way,
and enables mutations to be upgraded or downgraded in response to newly available data. …

Pharmacogenetics and pharmacogenomics: are they still promising?

A Pirazzoli, G Recchia - Pharmacological Research, 2004 - Elsevier
… for drug development, we observe a constant increase from 1996 [17]. We should conclude
that pharmacogenomics … in clinical practice within a few years. It may be, however, that some …

[HTML][HTML] Pharmacogenomics in practice: A review and implementation guide

D Kabbani, R Akika, A Wahid, AK Daly… - Frontiers in …, 2023 - frontiersin.org
… Next, we propose steps to be followed for developing and applying PGx in hospital clinical
practice. … In addition, guidelines on PGx data usage in drug development and labeling were …

Relevance of pharmacogenetics and pharmacogenomics in veterinary clinical practice: A review

A Vaidhya, K Ghildiyal, D Rajawat, SS Nayak… - Animal …, 2024 - Wiley Online Library
… As a result, the use of pharmacogenetics in drug discovery … In human medicine, the use of
genomics in drug development … , the application of pharmacogenetics for veterinary medication …