4 天前 - … The pharmacokinetic performance of NEB-LCNPs-ISG was also reflected in its
effective pharmacodynamic response over NEB-Susp. NEB-LCNPs-ISG resulted in a 2.2-folds …

4 天前 - … The aim of the current analyses was to develop a population pharmacokinetic
model for nepadutant in infants with colic, and a pharmacokinetic-pharmacodynamic model …

5 天前 - … Large pharmacokinetic (PK) variability of fluconazole has been reported in critically
ill … PK/pharmacodynamic (PD) target attainment (PTA) and cumulative fractions of response (…

5 天前 - … modeling deepens our understanding of drug responses, potentially leading to
more … -based pharmacokinetic (PBPK) modeling for predicting drug pharmacokinetics. PBPK …

6 天前 - … these cells show the lowest response to SAR’245, to then maximize response in
NK … Pharmacodynamic responses in NHP are comparable with different SAR’245 …

6 天前 - … (C avg_ss ) with the observed individual clinical response data from the Phase 2
and Phase 3 … Clinical response was measured using SRI response at Week 52. Patients who …

7 天前 - … (pharmacokinetics), the resulting treatment impact on the infecting pathogen (pharmacodynamics)
and host immune response (… rate), phage pharmacokinetics, phage–antibiotic …

7 天前 - … drug metabolism, plasma concentrations, and clinical response. A wide range of
clinical … significant challenges for clinical pharmacokinetics, necessitating close monitoring and …

7 天前 - … in pharmacokinetics and pharmacokinetic–pharmacodynamic (PK– PD) modeling
and simulation with a unique infrastructure to generate high- density drug response over time …

8 天前 - … responses or decrease clinical effectiveness. The two primary categories of DDIs are
pharmacokinetic and pharmacodynamic. … the mechanism of pharmacokinetic DDIs, with an …