… study compared the pharmacokinetics of two different dosing regimes of piperacillin and …
The present study gives pharmacokinetic evidence that continuous piperacillin/tazobactam …

… population pharmacokinetics of piperacillin in critically ill patients with sepsis during first
dose and at steady state. The data describe significantly different pharmacokinetic parameters …

… Therefore, we chose a loading dose of 4 g piperacillin and 1 g sulbactam before CI of 8 g
piperacillin/2 g sulbactam per 24 h. To achieve bactericidal activity, the serum concentrations …

… the pharmacokinetics of piperacillin administered by continuous infusion (CI) versus intermittent
bolus (IB) dosing … /pharmacokinetic (PK/PD) target attainment with each dosing strategy. …

… intermittent bolus dosing. Objective: This study compared the pharmacokinetics and
pharmacodynamics of piperacillin/tazobactam when administered as an intermittent bolus versus a …

… The purpose of this study was to characterize the pharmacokinetics of a single IV dose of
piperacillin in APD patients using 3 cycler exchanges over 8 hours and 2 ambulatory …

… of larger doses and an increased dosing … high doses of P/T are well tolerated even at doses
of piperacillin of 100 mg/kg for infants and children. However, the effect of these larger doses …

… CL and total V in the present patient population were also substantially lower than in other
patient populations who received piperacillin as intermittent bolus dosing, such as patients …

… on pharmacokinetic data from peer-reviewed literature. The desired proportion of the dosing
… T > MIC) for the intermittent bolus regimens was ≥40% for piperacillin/tazobactam and ≥60…

… as safe and effective as intermittent treatment with short intermittent infusions, and economic
outcomes were superior for continuous infusion. However, the short intermittent mode of …