Pharmacokinetics of propofol when given by intravenous infusion.

DJ Morgan, GA Campbell… - British journal of clinical …, 1990 - Wiley Online Library
… We have previously shown with iv bolus studies that the elimination of propofol is much …
prolonged iv infusion of propofol in seven patients who received continuous infusions of propofol

[HTML][HTML] Propofol: a review of its pharmacodynamic and pharmacokinetic properties and use as an intravenous anaesthetic

MS Langley, RC Heel - Drugs, 1988 - Springer
… clearance and initial volume of distribution of propofol are reduced in old age. Preliminary …
pharmacokinetics of propofol. Other anaesthetic drugs may affect the disposition of propofol — …

[HTML][HTML] Clinical pharmacokinetics and pharmacodynamics of propofol

MM Sahinovic, MMRF Struys, AR Absalom - Clinical pharmacokinetics, 2018 - Springer
Propofol is an intravenous hypnotic drug that is … propofol should only be administered by
practitioners trained and experienced in providing general anaesthesia. Many pharmacokinetic (…

[引用][C] Advances in propofol pharmacokinetics and pharmacodynamics

SL Shafer - Journal of clinical anesthesia, 1993 - Elsevier
… combining sufentanil with propofol to achieve total intravenous anesthesia (TIVR)… infusion
than from an alfentanil infusion, as shown in Figure 3. In summary, propofol’s pharmacokinetic

Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit

AE Rigby-Jones, JA Nolan, MJ Priston… - The Journal of the …, 2002 - pubs.asahq.org
… 12We hypothesized that the pharmacokinetics of propofol in neonates and young babies …
accurately describe the pharmacokinetics of propofol when given as a sedative infusion to very …

Population pharmacokinetics of propofol: a multicenter study

J Schüttler, H Ihmsen - The Journal of the American Society of …, 2000 - pubs.asahq.org
… In this study we performed a population pharmacokinetic analysis with data from five research
… The aims of this study were to estimate the pharmacokinetics of propofol with special …

Pharmacokinetics of propofol during and after long term continuous infusion for maintenance of sedation in ICU patients

GR Bailie, ID Cockshott, EJ Douglas… - British journal of …, 1992 - Elsevier
… sedated with propofol for 3 days. In this study we have measured the apparent steady state
propofol concentrations during sedative infusions and the decline in propofol concentration …

Pharmacokinetics of propofol administered by infusion in dogs undergoing surgery

A Nolan, J Reid - BJA: British Journal of Anaesthesia, 1993 - academic.oup.com
propofol is used by infusioninfusions, but in this study there was considerable interpatient
variation. Consequently, we decided to investigate the pharmacokinetics of propofol infusion

The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers

TW Schnider, CF Minto, PL Gambus… - The Journal of the …, 1998 - pubs.asahq.org
… on the infusion data only. We then used the infusion-based pharmacokinetics to predict the
… separate studies because the pharmacokinetics during the infusion were compared with the …

Disposition of propofol administered as constant rate intravenous infusions in humans

E Gepts, F Camu, ID Cockshott… - Anesthesia & …, 1987 - journals.lww.com
… Administered by intravenous infusion, propofol provided anesthesia … The pharmacokinetic
profile of the emulsion formulation of … We conclude that the pharmacokinetic profile of propofol