… Areas covered in this review: This review surveys literature on the diagnosis and pharmacological
management of TRD in light of recent developments. Evidence regarding commonly …

… academic pharmacology as a core discipline of translational medicine. The need for new
approaches … The reinvigoration of pharmacology can best be accomplished, in our opinion, by …

… Consequently, resulting drug concentration at the place of action and pharmacologic effect
… Volume of distribution of a drug depends on its pharmacological and physicochemical …

… approaches until the end of the 1800s, when the discovery of X-rays and their use for the
treatment of tumors provided the first modern therapeutic approach in … and pharmacology took …

… If this hypothesis is correct the consequences for modern medicine are profound, since it
would imply that our current understanding of pharmacology is an oversimplification. We …

… pharmacology, the development of new drugs, and to an improved quality of life for mankind.
Achieving leadership in health care in an era … of clinical pharmacology from pharmacology …

… pharmacologic approach than reversing tissue changes in existing disease. Administration
of pharmacologic … Potentially, this approach might also be utilized in conjunction with an …

… Clinical pharmacology is defined as the study of drugs in humans. Clinical pharmacologists
… The modern era of clinical pharmacology arose in response to the thalidomide crisis but …

… This begs the question, what is a good working definition for modern pharmacology? On
the … pertaining to pharmacology we rapidly realize that the definition of pharmacology varies …

… pharmacologic approach of any one drug acting on one target (eg, receptor, ion channel,
enzyme, or any of the multitude of system components). The biological system, in its normal …