… To test this, we investigated the effect of TubA, a highly selective inhibitor of HDAC6, in the
… pharmacological inhibition of HDAC6 deacetylase activity with TubA is beneficial to muscle …

… is the faster, more glycolytic phenotype (discussed in detail … potential of pharmacologically
evoked phenotypic plasticity in … of important phenotypic modifiers involved in skeletal muscle …

… muscle phenotype, we contrasted two competing influences known to exert opposite effects
on muscle phenotype, ie, calcineurin inhibition … leads to a slower phenotype with decreased …

… Overall, our work validates in worm, mouse, and human models that PARP inhibition may
be used to treat both genetic and acquired muscle dysfunction linked to defective …

… worsens the overall phenotype despite causing increased muscle mass and regeneration,
emphasizing the differential effects of myostatin and TGF-β signaling in muscle pathology. …

… We investigated the involvement of calcium-activated potassium channel (BK) in skeletal
muscle phenotype determination and response to acetazolamide, a BK opener. The BKs of slow…

… We conclude that β 2 -agonist induced muscle hypertrophy may be clinically limited as … of
the shift in muscle phenotype Decrements in skeletal muscle mass and functional capacity in …

… In the present study we investigated muscle hypertrophy and phenotypic shifts, as well as
the molecular response of components of the Akt/mTOR pathway (ie Akt, eukaryotic initiation …

… of individual smooth muscle cells (SMC). SMCs manifest phenotypic plasticity in response to
… Each phenotypic state is characterized by expression of a unique set of structural, contractile…

… skeletal muscle deconditioning. However, the question whether myostatin inhibition could
… Therefore, we hypothesized that inhibition of myostatin would improve skeletal muscle mass …