Integrated strategy of network pharmacology, molecular docking, HPLC-DAD and mice model for exploring active ingredients and pharmacological mechanisms of …

Y Jiang, M Zhong, H Zhan, X Tao, Y Zhang… - Journal of …, 2022 - Elsevier
… Thus, in the present study, the active ingredients and pharmacological mechanisms of PCP
against ALI were investigated by network pharmacology, molecular docking, HPLC-DAD and …

HPLC-DAD-UV analysis, anti-inflammatory and anti-neuropathic effects of methanolic extract of Sideritis bilgeriana (lamiaceae) by NF-κB, TNF-α, IL-1β and IL-6 …

MRM Cavalcanti, FRS Passos, BS Monteiro… - Journal of …, 2021 - Elsevier
… Thus, we aimed to evaluate the pharmacological effects of … In view of this, a chromatographic
method by HPLC-DAD-UV … the mechanisms of action of existing drugs, as many of these …

Identification and determination of the major constituents in traditional Chinese medicine Si-Wu-Tang by HPLC coupled with DAD and ESI–MS

H Zhang, P Shen, Y Cheng - Journal of pharmaceutical and biomedical …, 2004 - Elsevier
… However, although many TCM have been proven effective by modern pharmacological
studies and clinical trials, their bioactive constituents and the remedial mechanism are still not …

Simultaneous in vivo RP‐HPLCDAD quantification of multiple‐component and drug–drug interaction by pharmacokinetics, using 6,7‐dimethylesculetin, geniposide …

A Zhang, H Sun, X Wang, G Jiao… - Biomedical …, 2012 - Wiley Online Library
… The pharmacological effect of TCM is a result of the … of a non-MS detection HPLC assay
that meets the requirements of … be essential to investigate the mechanisms of synergism of …

HPLC-based activity profiling for pharmacologically and toxicologically relevant natural products–principles and recent examples

M Hamburger - Pharmaceutical biology, 2019 - Taylor & Francis
… , mostly in collaborative projects, HPLC profiling protocols for a … was known to be
pharmacologically promiscuous, with activity … HPLC activity profiling of an EtOAc extract of Piper …

[HTML][HTML] Applications of HPLC/MS in the analysis of traditional Chinese medicines

M Li, XF Hou, J Zhang, SC Wang, Q Fu… - Journal of Pharmaceutical …, 2011 - Elsevier
… This will facilitate our understanding of the mechanism of … effects of Chinese medicines and
pharmacological mecha-nisms. … by HPLC/DAD-MS techniques. A total of nine characteristic …

Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLCDAD–MS/MS

YH Wang, C Qiu, DW Wang, ZF Hu, BY Yu… - … of Pharmaceutical and …, 2011 - Elsevier
… In this paper, an HPLCDAD–MS/MS method is described for … pharmacological activities
of SMS. Therefore the active chemical constituents of SMS and its pharmacological mechanism

[HTML][HTML] Study of the active ingredients and mechanism of Sparganii rhizoma in gastric cancer based on HPLC-Q-TOF–MS/MS and network pharmacology

X Lu, Y Zheng, F Wen, W Huang, X Chen, S Ruan… - Scientific Reports, 2021 - nature.com
… Network pharmacology is a method for predicting the pharmacological mechanism of
drug treatments for diseases based on the theory of systems biology and the use of complex …

… profiling and identification of the absorbed constituents and metabolites of Paeoniae Radix Rubra decoction in rat plasma and urine by the HPLCDAD–ESI-IT-TOF …

J Liang, F Xu, YZ Zhang, S Huang, XY Zang… - … of Pharmaceutical and …, 2013 - Elsevier
… Recent pharmacological studies indicate that PRR has … the fields of phytochemistry,
pharmacology and clinical application. … obstacle for deeper pharmacological mechanism studies …

Qualitative and quantitative analysis of chemical constituents of Centipeda minima by HPLC-QTOF-MS & HPLC-DAD

C Chan, D Jin, N Dong, S Chen, DKW Mok - Journal of pharmaceutical and …, 2016 - Elsevier
… Recent pharmacological studies also showed that EBSC … in vitro, its underlying mechanisms
were associated with the up-… 1 sesquiterpene lactone by HPLC-DAD. Validation parameters …