The impact of network biology in pharmacology and toxicology
G Panagiotou, O Taboureau - SAR and QSAR in Environmental …, 2012 - Taylor & Francis
… toxicology approaches with global technologies that generate molecular, clinical and other
complementary data, network biology … In this review we describe how network biology can …
complementary data, network biology … In this review we describe how network biology can …
The effect of network biology on drug toxicology
L Gautier, O Taboureau, K Audouze - … drug metabolism & toxicology, 2013 - Taylor & Francis
… Following this trend, network biology was recently applied to pharmacological sources of …
interactions in order to develop a network pharmacology that could better explain the drug–…
interactions in order to develop a network pharmacology that could better explain the drug–…
Systems pharmacology to predict drug toxicity: integration across levels of biological organization
JPF Bai, DR Abernethy - … review of pharmacology and toxicology, 2013 - annualreviews.org
… , forming the blueprint for toxicological networks that can be described for each drug. These
individual networks are then expanded into a global toxicological network based on the …
individual networks are then expanded into a global toxicological network based on the …
[PDF][PDF] Studies on the network biology impact in pharmacology and toxicology
J Tao - Journal of Applied Health Sciences and Medicine, 2022 - jpub.org
… Network biology is a concept to deals with the biological process on a broader level. The …
as a network. The aims of network biology are to investigate the components of cellular …
as a network. The aims of network biology are to investigate the components of cellular …
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action
S Zhao, R Iyengar - … review of pharmacology and toxicology, 2012 - annualreviews.org
… systems biology approaches to pharmacology allows us to expand the definition of systems
pharmacology to include network analyses at multiple scales of biological organization and …
pharmacology to include network analyses at multiple scales of biological organization and …
… and toxicological insights of Astragalus in liver cancer based on network pharmacology: Integrating systems biology, drug interaction networks, and toxicological …
M Zou, Z Zheng, Z Xiahou, J Cao - Environmental Toxicology, 2024 - Wiley Online Library
… We utilized network pharmacology to unveil Astragalus's potential targets … the biological
processes and pathways involved. Further, we constructed protein–protein interaction networks …
processes and pathways involved. Further, we constructed protein–protein interaction networks …
New future of cell biology and toxicology: thinking deeper
J Gu, X Wang - Cell Biology and Toxicology, 2016 - Springer
… cell biology, genetic and epigenetic heterogeneity, drug discovery and development, and
molecular pharmacology and toxicology. The merger of cell biology and toxicology enables a …
molecular pharmacology and toxicology. The merger of cell biology and toxicology enables a …
Network pharmacology: the next paradigm in drug discovery
AL Hopkins - Nature chemical biology, 2008 - nature.com
… is found in the biological context to which they are applied. Therefore, understanding the
polypharmacology of a drug and its effect on biological networks and phenotype is essential if …
polypharmacology of a drug and its effect on biological networks and phenotype is essential if …
Data-intensive drug development in the information age: applications of Systems Biology/Pharmacology/Toxicology
N Kiyosawa, S Manabe - The Journal of Toxicological Sciences, 2016 - jstage.jst.go.jp
… research, namely Systems Toxicology, should considerably improve the predictability of …
preclinical toxicology studies. Systems Biology/Pharmacology/Toxicology models can be …
preclinical toxicology studies. Systems Biology/Pharmacology/Toxicology models can be …
Fitting tissue chips and microphysiological systems into the grand scheme of medicine, biology, pharmacology, and toxicology
DE Watson, R Hunziker… - Experimental biology and …, 2017 - journals.sagepub.com
… MPS to problems in medicine, biology, pharmacology, and toxicology, and another EBM MPS
… human disease biology/pharmacology, ADME-PK-clinical pharmacology, and toxicology. …
… human disease biology/pharmacology, ADME-PK-clinical pharmacology, and toxicology. …
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