… could be administered safely with other childhood vaccines8,11 and provided protection
against severe malaria.Here, we report the initial results of an ongoing phase 3 trial being …

… It was developed to reduce clinical and severe malaria … phase 3 trial, which showed that
during 12 months of follow-up, RTS,S/AS01 had an efficacy against clinical and severe malaria …

Background The efficacy and safety of the RTS,S/AS01 candidate malaria vaccine during 18
months of follow-up have been published previously. Herein, we report the final results from …

… Currently, there is no licensed malaria vaccine, but RTS,S/AS01, the most advanced
malaria vaccine candidate, is undergoing phase 3 clinical trials (the last stage of testing before …

… Efficacy and safety of RTS,S/AS01 malaria vaccine with or … results of a phase 3, individually
randomised, controlled trial. … First results of phase 3 trial of RTS,S/AS01 malaria vaccine …

… malaria vaccine, R21/Matrix-M, had over 75% efficacy against clinical malaria with seasonal
administration in a phase 2b trial … and efficacy of the vaccine in a phase 3 trial enrolling over …

… Added value of this study This study includes data from a large phase 3 trial spanning a
wide range of malaria transmission intensities. The …

… (Montanide ISA 720, aluminum hydroxide) phase I clinical trial we evaluated the safety and
… This led to a reduction in the subsequent vaccine doses in four of the groups. No vaccine-…

… on mortality in phase III trials has also been observed for other vaccines; no reduction …
vaccinated with the oral, live attenuated human rotavirus vaccine compared to placebo-vaccinated …

… vaccination) from the RTS,S/AS01 E phase 3 clinical trial who received 3 doses of RTS,S/AS01
E or a comparator vaccine … 1 month post primary immunization. Two sites with different …