Genes as cues: phenotypic integration of genetic and epigenetic information from a Darwinian perspective

SRX Dall, JM McNamara, O Leimar - Trends in Ecology & Evolution, 2015 - cell.com
… The integration systems themselves are under genetic control … framework for linking genetic
and phenotypic variation from an … can elucidate genetic influences on phenotypic variation in …

[HTML][HTML] A symbiotic liaison between the genetic and epigenetic code

H Heyn - Frontiers in Genetics, 2014 - frontiersin.org
… our knowledge about phenotype biology … genetic and epigenetic code are widely unknown,
their identification suggested causal connections between genetic and epigenetic information

An integrated epigenetic and genetic approach to common human disease

HT Bjornsson, MD Fallin, AP Feinberg - TRENDS in Genetics, 2004 - cell.com
… that determine epg or genes the directly affect disease phenotypes. For clarity, we have … ind
to genes that affect disease independently of epigenetics and the subscript epg to genes that …

Phenotypic plasticity and epigenetic marking: an assessment of evidence for genetic accommodation

CD Schlichting, MA Wund - Evolution, 2014 - academic.oup.com
… of phenotypic plasticity and (2) the environmental sensitivity of epigenetic modification.
We assess the strength of empirical evidence for roles of phenotypic plasticity and epigenetic

The integrated phenotype

CJ Murren - Integrative and Comparative Biology, 2012 - academic.oup.com
Phenotypic integration refers to the relationships among multiple characters of a complex
phenotype… In this review, I summarize a brief history of the concept of phenotypic integration in …

Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis

S Diels, W Vanden Berghe, W Van Hul - Obesity Reviews, 2020 - Wiley Online Library
… factors through epigenetic regulation. This suggests that a combined analysis of genetic and
epigenetic variation may be more effective in characterizing the obesity phenotype. To date, …

Quantitative genetic models for development, epigenetic selection, and phenotypic evolution

DE Cowley, WR Atchley - Evolution, 1992 - Wiley Online Library
… ofa generalized quantitative genetic model of growth and development are examined. In
particular, we explore the role of intrinsic genetic and epigenetic phenomena in understanding …

Detection vs. selection: integration of genetic, epigenetic and environmental cues in fluctuating environments

JM McNamara, SRX Dall, P Hammerstein… - Ecology …, 2016 - Wiley Online Library
… These include genetic effects, transgenerational epigenetic … in which cues are integrated to
determine mature phenotypes in … The mother's phenotype and a quantitative genetic effect act …

Critical issues in the inclusion of genetic and epigenetic information in prevention and intervention trials

SJ Latendresse, R Musci, BS Maher - Prevention Science, 2018 - Springer
genetic and epigenetic indicators as part of their investigations, harvesting the wealth of
information … statistical modelling of genetic, polygenic, and epigenetic measures in longitudinal …

[图书][B] Epigenetics: linking genotype and phenotype in development and evolution

B Hallgrímsson, BK Hall - 2011 - books.google.com
gene sequences are examples of epigenetics at the level of the structure and function of the
gene, sometimes referred to as the “phenotype” of the gene… and phenotype established over …