Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine
VE Kagan, GG Borisenko, YY Tyurina, VA Tyurin… - Free Radical Biology …, 2004 - Elsevier
… cyt c actuates both of these oxidative roles through a uniform mechanism: its … oxidizing the
activating phospholipids. We also show that this new concept is compatible with a leading role …
activating phospholipids. We also show that this new concept is compatible with a leading role …
The Plasma Membrane Is the Site of Selective Phosphatidylserine Oxidation During Apoptosis: Role of Cytochrome c
YY Tyurina, K Kawai, VA Tyurin, SX Liu… - … and Redox Signaling, 2004 - liebertpub.com
… oxidation of PS may be mediated via the cytochrome c. To investigate the relationship between
a release of cytochrome c … of exogenous cytochrome c to induce selective oxidation of PS …
a release of cytochrome c … of exogenous cytochrome c to induce selective oxidation of PS …
[HTML][HTML] Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis
VE Kagan, JP Fabisiak, AA Shvedova, YY Tyurina… - FEBS letters, 2000 - Elsevier
… phosphatidylserine externalization. We speculate that selective phosphatidylserine oxidation
could affect phosphatidylserine … Thus, cytochrome c-mediated phosphatidylserine oxidation …
could affect phosphatidylserine … Thus, cytochrome c-mediated phosphatidylserine oxidation …
Peroxidation and externalization of phosphatidylserine associated with release of cytochrome c from mitochondria
J Jiang, BF Serinkan, YY Tyurina, GG Borisenko… - Free Radical Biology …, 2003 - Elsevier
… preferential PS oxidation are not well understood. We hypothesized that cytochrome c (cyt c)
… To further elucidate the role of cyt c in PS oxidation, we integrated it into cyt c null (Cyt c −/−) …
… To further elucidate the role of cyt c in PS oxidation, we integrated it into cyt c null (Cyt c −/−) …
Cytochrome c release is required for phosphatidylserine peroxidation during fas‐triggered apoptosis in lung epithelial A549 cells
… Since oxidative stress during apoptosis is largely due to disrupted electron transport in … of
cytochrome c (cyt c) from mitochondria into cytosol, we hypothesized that this specific oxidative …
cytochrome c (cyt c) from mitochondria into cytosol, we hypothesized that this specific oxidative …
Thiol Oxidation Enforces Phosphatidylserine Externalization in Apoptosis-Sensitive and -Resistant Cells Through a Δψm/Cytochrome c Release-Dependent …
AJ Forsberg, VE Kagan, AJ Schroit - Antioxidants and Redox …, 2004 - liebertpub.com
… might be due to the inability of the cells to oxidize critical sulfhydryls. Here we report that
ROS likely play a critical role in sulfhydryl oxidation because ROS-dependent intrinsic apoptosis…
ROS likely play a critical role in sulfhydryl oxidation because ROS-dependent intrinsic apoptosis…
Phospholipid signaling in apoptosis: peroxidation and externalization of phosphatidylserine
YY Tyurina, AA Shvedova, K Kawai, VA Tyurin… - Toxicology, 2000 - Elsevier
… in which cytochrome c released from mitochondria by oxidative stress binds to phosphatidylserine
located at the cytoplasmic surface of the plasma membrane and induces its oxidation. …
located at the cytoplasmic surface of the plasma membrane and induces its oxidation. …
Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis?
YY Tyurina, VA Tyurin, Q Zhao, M Djukic… - Biochemical and …, 2004 - Elsevier
… oxidation of phosphatidylserine (PS) … PS oxidation stimulates its externalization via its effects
on aminophospholipid translocase (APT) or by enhanced PS scrambling, action of oxidized …
on aminophospholipid translocase (APT) or by enhanced PS scrambling, action of oxidized …
A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated …
VE Kagan, B Gleiss, YY Tyurina, VA Tyurin… - The Journal of …, 2002 - journals.aai.org
… of phospholipid asymmetry and attendant externalization of phosphatidylserine (PS) 4 on the
outer … (ROS), resulting in part from cytochrome c departure from mitochondria and attendant …
outer … (ROS), resulting in part from cytochrome c departure from mitochondria and attendant …
[HTML][HTML] Mechanisms underlying production and externalization of oxidized phosphatidylserine in apoptosis: involvement of mitochondria
A Yamashita, H Morikawa, N Tajima… - Yonago Acta …, 2012 - ncbi.nlm.nih.gov
… Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with
cardiolipin and phosphatidylserine. Free Radic Biol Med 2004; 37: 1963–1985 [PubMed] [Google …
cardiolipin and phosphatidylserine. Free Radic Biol Med 2004; 37: 1963–1985 [PubMed] [Google …
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