… classes of photosensitizers the antifungal action of hypericin (Hyp) stands out due to its …
characteristics, and optimal alternative drug deliveries that promote the photodynamic action of …

… In brief, PDT requires the synergy of a photoactive drug, light at the appropriate wavelength
and molecular oxygen for the production of either 1 O 2 (18) by direct energy transfer from …

… In order to better understand how the photodamage of the cell is realized, it seems relevant
to consider where the principle sites of subcellular accumulation of a photoactive drug might …

… Hypericin (HY) … photoactivity than free HY (P < 0.05) and HY-loaded PLGA nanoparticles.
Increasing the loading of HY on PLA nanoparticles had a negative effect on their photoactivity …

… containing heterocycles does not interfere with the photoactivity of the parent system 1 [80].
Mono-substitution of hypericin requires a higher synthesis effort due to the demands of an …

… The objective of this study was to prepare and characterise hypericin-loaded solid lipid
nanoparticles (Hy-SLN) for use in photodynamic therapy (PDT). SLN were prepared using the …

… In the last three decades, hypericin has also become the subject of … of hypericin as an
antiretroviral drug in HIV-infected adults was designed with multiple high doses of pure hypericin …

Fluorescence binding measurements and molecular modeling were employed to study the
interaction of hypericin (Hyp) with human (HSA), rat (RSA), and bovine (BSA) serum albumins…

… of polyethyleneglycol substituted derivatives like hypericin-PEG-3 (28) [69,70]. This compound
showed an enhanced hydrophilicity but a lower photoactivity and also a limited cellular …

… 1) is a natural photoactive pigment which plays a role as an effective photoreceptor [1] in
some plants of the Hypericum species (the most common of which is Saint John's Wort) and …