Effect of photodynamic inactivation of Escherichia coli by hypericin

J Zhang, F Zhang, Q Tang, C Xu, X Meng - World Journal of Microbiology …, 2018 - Springer
… The present study has focused on the effects of hypericin (Hyp) based photodynamic
inactivation (PDI) of Escherichia coli (E. coli). To evaluate the efficiency of Hyp based PDI of E. …

[HTML][HTML] Photodynamic therapy using topically applied hypericin: comparative effect with methyl-aminolevulinic acid on UV induced skin tumours

A Boiy, R Roelandts, PAM De Witte - Journal of Photochemistry and …, 2011 - Elsevier
… In contrast to PpIX, hypericin, a photo-active dianthraquinone dye with a broad action
spectrum originating from the herb Hypericum perforatum (St. John’s wort) [15], [16], is very …

Phototoxicity in Human Retinal Pigment Epithelial Cells Promoted by Hypericin, a Component of St. John's Wort

AR Wielgus, CF Chignell, DS Miller… - Photochemistry and …, 2007 - Wiley Online Library
… In conclusion, we have determined that the photoactive component of SJW, hypericin,
induces oxidative stress and lipid peroxidation in hRPE cells in vitro. There have been reports of …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Hypericin (Hy) is a potent lipid-soluble photosensitiser with … The physicochemical properties,
photoactivity, ex vivo drug … ), 396 fold higher photoactivity, 7 fold higher skin drug deposition, …

Chemiluminescent activation of the antiviral activity of hypericin: a molecular flashlight.

S Carpenter, MJ Fehr, GA Kraus… - Proceedings of the …, 1994 - National Acad Sciences
Hypericin is a naturally occurring photosensitizer that … may preclude the use of hypericin
and other photosensitizers as … antiviral activity of hypericin. Light-induced virucidal activity of …

Hypericin and 5-aminolevulinic acid-induced protoporphyrin IX induce enhanced phototoxicity in human endometrial cancer cells with non-coherent white light

X Schneider-Yin, A Kurmanaviciene, M Roth… - Photodiagnosis and …, 2009 - Elsevier
… In the present study, using purified hypericin, as the major photoactive compound of St.
John's wort, we were able to confirm that hypericin increases the phototoxic effect mediated by 5-…

Hypericin-based photodynamic therapy displays higher selectivity and phototoxicity towards melanoma and squamous cell cancer compared to normal keratinocytes …

M Woźniak, M Nowak-Perlak - International Journal of Molecular Sciences, 2023 - mdpi.com
… Taking into account that hypericin has an increased cytotoxic effect combined with PDT,
recent data show the potential of natural substances in designing photoactive agents. Hypericin

[HTML][HTML] Effective transport of aggregated hypericin encapsulated in SBA-15 nanoporous silica particles for photodynamic therapy of cancer cells

V Pevná, Ľ Zauška, A Benziane, G Vámosi… - … of Photochemistry and …, 2023 - Elsevier
… f) Drug release curves of hypericin from SBA-15 + hypericin material in FBS media in
time intervals 0-4 h with 30 min step (inset shows a calibration curve of hypericin). (For …

[HTML][HTML] Effects of hypericin encapsulated on Pluronic F127 photodynamic therapy against triple negative breast cancer

MVF De Souza, CS Shinobu-Mesquita… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
… Additionally, it has been suggested that the type II mechanism is the one to play a major
role in the biological photoactivity of HYP, which is also in line with our results. Taken together, …

[HTML][HTML] Response surface method optimization of a novel Hypericin formulation in P123 micelles for colorectal cancer and antimicrobial photodynamic therapy

MC Montanha, LL Silva, FBB Pangoni, GB Cesar… - … of Photochemistry and …, 2017 - Elsevier
The photodynamic properties of Hypericin (Hyp) may be used as an alternative treatment for
malignancies of the lower gastrointestinal tract and for the prevention of surgical-site …