… Hypericin, a herbal photosensitizer which is the main photoactive constituent from St. Johns
wort was purchased from Invitrogen (Basel, Switzerland). A 1 mg was dissolved in 1 mL 100…

… of hypericin … hypericin substantially reduce virus infectivity on Vero E6 cells, but a partial
effect is also observed in dark conditions, suggesting multiple mechanisms of action for this drug…

… Our findings indicate that drugs in combinations did not show any mutagenic or cytotoxic
activity. Another important finding refers to the action of given substances (photoactivated …

… Hypericin usually co-purifies with a congener, pseudohypericin, with the two forming up to
0.… from hypericin by a single hydroxyl group substitution in one methyl group. Hypericin is also …

… Proteins are highly biocompatible and warrant good bioavailability of the photoactive
drug. We recently proposed the use of proteins such as apomyoglobin (apoMb) and β-lactoglobulin …

Multifunctional P123 micelle linked covalently with spermine (SM) and folic acid (FA) was
developed as a drug delivery system of hypericin (HYP). The chemical structures of the …

… Hypericin (Hy) compound presents a high photoactivity in photodynamic therapy (PDT),
photodiagnosis and theranostics applications. The maintenance of this compound in monomeric …

… This triplet state is the photoactive state, which may generate cytotoxic species by … (Photofrin
II and hypericin) in solvents of different polarity and for different con− centration of the dye. …

… photogenotoxic and phototoxic effects of hypericin photoactive in V79 cells. … hypericin, our
findings allow us to generate discussions about the cytotoxic action mechanism of hypericin …

… of hypericin on the conformation and catalytic activity of the protein has also been proven to
be strongly dependent on the irradiation time, the hypericin … light irradiation on hypericin, the …