Living Bacteria‐Based Immuno‐Photodynamic Therapy: Metabolic Labeling of Clostridium butyricum for Eradicating Malignant Melanoma

L Shi, X Liu, Y Li, S Li, W Wu, X Gao, B Liu - Advanced Science, 2022 - Wiley Online Library
… the whole tumor through conventional treatment. Herein, a strategy of metabolic engineering
labeled anaerobic oncolytic bacteria (Clostridium butyricum) is demonstrated to achieve the …

The use of Clostridium in cancer therapy: a promising way

A Yaghoubi, K Ghazvini, M Khazaei… - … and Research in …, 2022 - journals.lww.com
In recent decades, the traditional cancer therapeutic agents such as surgery, radiotherapy,
and chemotherapy have failed. One of the main reasons for repeated failures in the field of …

[HTML][HTML] Novel insights into the role of Clostridium novyi‑NT related combination bacteriolytic therapy in solid tumors

X Feng, P He, C Zeng, YH Li, SK Das… - Oncology …, 2021 - spandidos-publications.com
Clostridium-directed antibody therapy was combined with the oncolytic properties of
Clostridium and the target selectivity of antibody therapeutics to target the most resistant regions in …

Immunogenic cell death: A link between gut microbiota and anticancer effects

W Chen, S Wang, Y Wu, X Shen, Z Guo, Q Li… - Microbial …, 2020 - Elsevier
… , radiotherapy and photodynamic therapy are capable of … Jia et al. found that Clostridium
butyricum regulated intestinal … -producing bacteria such as Clostridium butyricum, etc. serve …

Photodynamic therapy-improved oncolytic bacterial immunotherapy with FAP-encoding S. typhimurium

Y Guo, M Song, X Liu, Y Chen, Z Xun, Y Sun… - Journal of Controlled …, 2022 - Elsevier
… the oncolytic bacterium Clostridium butyricum labeled with a D-alanine–TPApy photosensitizer
with light illumination for 9 days demonstrated decent antitumor activity in the treatment of …

The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt+Treg and PD-1 blockade efficacy

T Paz Del Socorro, K Oka, O Boulard, M Takahashi… - Gut …, 2024 - Taylor & Francis
… A pilot clinical trial has reflected optimistic association between supplementation with
Clostridium butyricum MIYAIRI 588 (CBM588) and ICI efficacy in NSCLC. However, it remains to …

[HTML][HTML] Recent advances in bacteria-based cancer treatment

X Wei, M Du, Z Chen, Z Yuan - Cancers, 2022 - mdpi.com
… Spores-dex is prepared by the chemical reaction between Clostridium butyricum and glucan…
photodynamic therapy, the internal light source of D-fluorescein had better photodynamic

[PDF][PDF] Therapeutic Effect of Micro-Ecologics Combined with Blue Light Irradiation on Neonatal Jaundice: Randomized Control Trial

GAO KE, SH ABBAS, ALI FAHEEM, M ZEESHAN… - pjmhsonline.com
… that Clostridium butyricum capsules combined with blue light irradiation had obvious
therapeutic … Effect of short time multiple blue light therapy in the treatment of neonatal jaundice …

Bacteria-driven bio-therapy: from fundamental studies to clinical trials

Y Yu, S Lin, Z Chen, B Qin, Z He, M Cheng, M Sun… - Nano Today, 2023 - Elsevier
butyricum MIYAIRI 588 was isolated from the soil. Since C. butyricum MIYAIRI 588 demonstrated
the function of maintaining the … butyricum to avoid the risk of infection during treatment. …

[HTML][HTML] Recent advances in bacteria-mediated cancer therapy

S Liang, C Wang, Y Shao, Y Wang, D Xing… - … in Bioengineering and …, 2022 - frontiersin.org
therapy, magnetothermal therapy, and photodynamic therapy, while promoting the antitumor
efficiency of synergistic cancer therapies. … butyricum could exert photodynamic effects under …