Targeting to macrophages: role of physicochemical properties of particulate carriers—liposomes and microspheres—on the phagocytosis by macrophages

F Ahsan, IP Rivas, MA Khan, AIT Suárez - Journal of controlled release, 2002 - Elsevier
… the physicochemical properties of particulate carriers intended to deliver biologically active
agents to macrophages. … Various physicochemical parameters such as surface charge, size, …

Tunable particles alter macrophage uptake based on combinatorial effects of physical properties

A Garapaty, JA Champion - Bioengineering & translational …, 2017 - Wiley Online Library
physical properties of particles in altering phagocytic interactions. The combinatorial effect of
physical properties … on Fc receptor mediated macrophage interactions by fabrication of layer…

Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self'CD47, and target physical properties

NG Sosale, KR Spinler, C Alvey, DE Discher - Current opinion in …, 2015 - Elsevier
… of the FcγR phagocytosis pathway. Because macrophages and phagocytic dendritic cells can
… Cooperative binding of IgG Fc domains to macrophage FcγR receptors triggers phagocytic

Mechanisms of phagocytosis in macrophages

A Aderem, DM Underhill - Annual review of immunology, 1999 - annualreviews.org
phagocytes exist that lead to the enhancement of both rate andefficiency of particle internalization.
The study of phagocytosis … limit our focus to phagocytic mechanisms in macrophages. …

Phagocytosis and phagosomal fate of surface-modified microparticles in dendritic cells and macrophages

L Thiele, HP Merkle, E Walter - Pharmaceutical research, 2003 - Springer
… ) to study the mechanisms of phagocytosis and assess the residence of phagocytosed MP. …
In vitro phagocytosis and monocytemacrophage activation with poly(lactide) and poly(lactide…

Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking

X Duan, Y Li - Small, 2013 - Wiley Online Library
… of physicochemical properties on nanoparticle transport behavior in blood, their uptake and
clearance by macrophages … in vivo, their phagocytosis by macrophage and the subsequent …

Effects of microparticle size and Fc density on macrophage phagocytosis

P Pacheco, D White, T Sulchek - PloS one, 2013 - journals.plos.org
… to a greater percentage of the macrophage population. This study is the first … physical and
biological properties of Fc density and microparticle size that initiate macrophage phagocytosis

Phagocytosis dynamics depends on target shape

D Paul, S Achouri, YZ Yoon, J Herre, CE Bryant… - Biophysical journal, 2013 - cell.com
… requires insight into both its biochemical and physical aspects. One of the ways to explore
the physical mechanism of phagocytosis is to probe whether and how the target properties (eg…

Effect of the size and surface charge of polymer microspheres on their phagocytosis by macrophage

Y Tabata, Y Ikada - Biomaterials, 1988 - Elsevier
phagocytic cells and induce host defence reactions. The macrophage is the most important
phagocytic … Therefore, it is very important to study the interaction between macrophage and …

Role of particle size in phagocytosis of polymeric microspheres

JA Champion, A Walker, S Mitragotri - Pharmaceutical research, 2008 - Springer
… Herein, using rat alveolar macrophages as model macrophages and polystyrene particles
(1–6 μm) as model microspheres, we report on the dependence of phagocytosis on size and …