Metabolic coordination of physiological and pathological cardiac remodeling

AA Gibb, BG Hill - Circulation research, 2018 - Am Heart Assoc
pathological remodeling. This review integrates knowledge of different forms of cardiac
remodeling … glucose metabolism may fortify cardiac health or promote (mal)adaptive myocardial …

Cardiac remodeling: New insights in physiological and pathological adaptations

L Roever, AC Palandri Chagas - Frontiers in Physiology, 2017 - frontiersin.org
Cardiac remodeling (CR) is a complex process involving cardiac myocyte growth and death,
vascular rarefaction, fibrosis, inflammation, and electrophysiological alterations (Burchfield …

Molecular pathways underlying cardiac remodeling during pathophysiological stimulation

I Kehat, JD Molkentin - Circulation, 2010 - Am Heart Assoc
… , and pathological cardiac remodeling. Reciprocally, introduction of angiogenic factors
during pressure overload enhances the increase in the number of microvessels, preserving the …

[HTML][HTML] Cardiac remodeling: concepts, clinical impact, pathophysiological mechanisms and pharmacologic treatment

PS Azevedo, BF Polegato, MF Minicucci… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Cardiac remodeling is defined as a group of molecular, … and clinical implications of
cardiac remodeling, and the … pharmacological treatment of cardiac remodeling, which can be …

Mechanisms for the transition from physiological to pathological cardiac hypertrophy

CJ Oldfield, TA Duhamel… - … journal of physiology and …, 2020 - cdnsciencepub.com
… upregulated, while pathological cardiac hypertrophy is associated … of physiological cardiac
hypertrophy to pathological cardiac … of pathological cardiac remodeling, cardiac fibrosis, and …

The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling

A Calderone - Frontiers in Cell and Developmental Biology, 2018 - frontiersin.org
… The present review will highlight the biological role of nestin (+) -cells during physiological
and pathological cardiovascular remodeling and discuss the biological impact of the …

Distinct lipidomic profiles in models of physiological and pathological cardiac remodeling, and potential therapeutic strategies

YK Tham, K Huynh, NA Mellett, DC Henstridge… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… of lipid species in models of pathological cardiac remodeling, but to our knowledge…
physiological remodeling. A major lipid class shown to be upregulated in humans and mice in …

Physiological and pathological cardiac hypertrophy

I Shimizu, T Minamino - Journal of molecular and cellular cardiology, 2016 - Elsevier
… leading to maladaptive cardiac remodeling and heart failure. This review describes the key
molecules and cellular responses involved in physiological/pathological cardiac hypertrophy. …

How cardiomyocytes sense pathophysiological stresses for cardiac remodeling

ZK Haque, DZ Wang - Cellular and Molecular Life Sciences, 2017 - Springer
… Interestingly, this group observed suppression of NFAT activity upon physiologic cardiac
remodeling (ie, exercise-induced hypertrophy). Upon activation, calcineurin binds and …

Pathological cardiac remodeling seen by the eyes of proteomics

DP Gomez-Mendoza, AC Lara-Ribeiro… - … et Biophysica Acta (BBA …, 2021 - Elsevier
pathological cardiac remodeling induced by ischemic injury - ie, MI - and high blood
pressure-induced cardiac … signatures from the pathological cardiac remodeling that may be …